Found 456 with Last Name = 'ramsbeck' and Initial = 'd' 
Affinity DataKi: 4.40nM ΔG°: -48.5kJ/mole IC50: 235nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrate. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 4.60nM ΔG°: -48.4kJ/mole IC50: 46.1nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrate. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
TargetMeprin A subunit beta(Homo sapiens)
Fraunhofer Institute For Cell Therapy and Immunology Izi
Curated by ChEMBL
Fraunhofer Institute For Cell Therapy and Immunology Izi
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of recombinant human meprin beta expressed in baculovirus infected Sf9 insect cells using (MCA)-EDEDED-(K-epsilon-dnp) as substrate by flu...More data for this Ligand-Target Pair
Affinity DataKi: 10nM ΔG°: -46.4kJ/mole IC50: 80nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 11.9nM ΔG°: -46.0kJ/mole IC50: 73.1nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrate. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 12.5nM IC50: 160nMAssay Description:Spectrophotometic Assay: This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spect...More data for this Ligand-Target Pair
Affinity DataKi: 12.5nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
Affinity DataKi: 13.9nM ΔG°: -45.6kJ/mole IC50: 72.5nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrate. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 18.8nM ΔG°: -44.8kJ/mole IC50: 85.8nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrate. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
TargetMeprin A subunit beta(Homo sapiens)
Fraunhofer Institute For Cell Therapy and Immunology Izi
Curated by ChEMBL
Fraunhofer Institute For Cell Therapy and Immunology Izi
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Inhibition of recombinant human meprin beta expressed in baculovirus infected Sf9 insect cells using (MCA)-EDEDED-(K-epsilon-dnp) as substrate by flu...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Escherichia coli DH5alpha using H-Gln-AMC as substrate by fluorometric analysis in presence of py...More data for this Ligand-Target Pair
Affinity DataKi: 33.6nM IC50: 170nMAssay Description:Spectrophotometic Assay: This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spect...More data for this Ligand-Target Pair
Affinity DataKi: 33.6nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
Affinity DataKi: 37.4nM IC50: 238nMAssay Description:Spectrophotometic Assay: This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spect...More data for this Ligand-Target Pair
Affinity DataKi: 37.4nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
Affinity DataKi: 40nM ΔG°: -42.9kJ/mole IC50: 450nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 40.8nM IC50: 254nMAssay Description:Spectrophotometic Assay: This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spect...More data for this Ligand-Target Pair
Affinity DataKi: 40.8nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
Affinity DataKi: 50nM ΔG°: -42.4kJ/mole IC50: 680nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 53.5nM IC50: 297nMAssay Description:Spectrophotometic Assay: This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spect...More data for this Ligand-Target Pair
Affinity DataKi: 53.5nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
Affinity DataKi: 58.8nM IC50: 240nMAssay Description:Spectrophotometic Assay: This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spect...More data for this Ligand-Target Pair
Affinity DataKi: 58.8nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
Affinity DataKi: 60nM ΔG°: -41.9kJ/mole IC50: 400nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 60nM ΔG°: -41.9kJ/mole IC50: 590nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 62.5nM IC50: 482nMAssay Description:Spectrophotometic Assay: This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spect...More data for this Ligand-Target Pair
Affinity DataKi: 62.5nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
Affinity DataKi: 75nM IC50: 397nMAssay Description:Spectrophotometic Assay: This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spect...More data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
Affinity DataKi: 80nM ΔG°: -41.2kJ/mole IC50: 290nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 80nM ΔG°: -41.2kJ/mole IC50: 480nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 80nM ΔG°: -41.2kJ/mole IC50: 480nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 80nM ΔG°: -41.2kJ/mole IC50: 490nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 80nM ΔG°: -41.2kJ/mole IC50: 760nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Escherichia coli DH5alpha using H-Gln-AMC as substrate by fluorometric analysis in presence of py...More data for this Ligand-Target Pair
Affinity DataKi: 90nM ΔG°: -40.9kJ/mole IC50: 360nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 100nM ΔG°: -40.6kJ/mole IC50: 220nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 100nM ΔG°: -40.6kJ/mole IC50: 470nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 106nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Escherichia coli DH5alpha using H-Gln-AMC as substrate by fluorometric analysis in presence of py...More data for this Ligand-Target Pair
Affinity DataKi: 107nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Escherichia coli DH5alpha using H-Gln-AMC as substrate by fluorometric analysis in presence of py...More data for this Ligand-Target Pair
Affinity DataKi: 110nM ΔG°: -40.4kJ/mole IC50: 640nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 120nM ΔG°: -40.2kJ/mole IC50: 520nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 120nM ΔG°: -40.2kJ/mole IC50: 530nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 120nM ΔG°: -40.2kJ/mole IC50: 550nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 120nM ΔG°: -40.2kJ/mole IC50: 560nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 120nM ΔG°: -40.2kJ/mole IC50: 570nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 130nM ΔG°: -40.0kJ/mole IC50: 800nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 130nM ΔG°: -40.0kJ/mole IC50: 830nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Affinity DataKi: 139nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Escherichia coli DH5alpha using H-Gln-AMC as substrate by fluorometric analysis in presence of py...More data for this Ligand-Target Pair
Affinity DataKi: 140nM ΔG°: -39.8kJ/mole IC50: 570nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
