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Found 3 Enz. Inhib. hit(s) with Target = 'Glutaminyl-peptide cyclotransferase' and Ligand = 'BDBM98186'
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM98186(US8486940, 73 | US9650362, 73)
Affinity DataKi:  33.6nM IC50:  170nMAssay Description:Spectrophotometic Assay: This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spect...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM98186(US8486940, 73 | US9650362, 73)
Affinity DataKi:  33.6nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM98186(US8486940, 73 | US9650362, 73)
Affinity DataIC50:  170nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
In DepthDetails US Patent