TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Non-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Non-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Non-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 49nMAssay Description:Non-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 64nMAssay Description:Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 211nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 244nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 253nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 293nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 295nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 301nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 304nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 309nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 348nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 495nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 525nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 758nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 820nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 926nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.04E+3nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.73E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.82E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.07E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.07E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.16E+3nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair