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Found 65 with Last Name = 'smart' and Initial = 'd'
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218750(CHEMBL299498)
Affinity DataKi:  2.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218751(CHEMBL300835)
Affinity DataKi:  4nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219319(CHEMBL438925)
Affinity DataKi:  13nMAssay Description:Binding affinity to Orexin receptor type 1 was determined using laser scanning cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218748(CHEMBL301209)
Affinity DataKi:  13nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218752(CHEMBL56557)
Affinity DataKi:  16nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218750(CHEMBL299498)
Affinity DataKi:  25nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218749(CHEMBL54062)
Affinity DataKi:  32nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218745(CHEMBL57135)
Affinity DataKi:  32nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218749(CHEMBL54062)
Affinity DataKi:  32nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218748(CHEMBL301209)
Affinity DataKi:  50nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218745(CHEMBL57135)
Affinity DataKi:  50nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218752(CHEMBL56557)
Affinity DataKi:  50nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218751(CHEMBL300835)
Affinity DataKi:  79nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218747(CHEMBL417753)
Affinity DataKi:  79nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218747(CHEMBL417753)
Affinity DataKi:  126nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50445184(CHEMBL412459)
Affinity DataKi:  269nMAssay Description:Binding affinity to Orexin receptor type 1 was determined using laser scanning cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218746(CHEMBL59266)
Affinity DataKi:  631nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218746(CHEMBL59266)
Affinity DataKi:  631nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50384416(CHEMBL2111553 | CHEMBL291536 | SB-334867)
Affinity DataKi:  3.98E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50384416(CHEMBL2111553 | CHEMBL291536 | SB-334867)
Affinity DataKi: <5.01E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219318(CHEMBL262404)
Affinity DataKi:  6.61E+4nMAssay Description:Binding affinity to Orexin receptor type 1 was determined using laser scanning cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20469(3-{2-[ethyl(3-methylphenyl)amino]ethyl}-1-phenylur...)
Affinity DataEC50:  63nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20470(3-{2-[ethyl(3-methylphenyl)amino]ethyl}-1-(2-methy...)
Affinity DataEC50:  126nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20471(3-{2-[ethyl(3-methylphenyl)amino]ethyl}-1-(2-fluor...)
Affinity DataEC50:  158nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM20472(1-(2-chlorophenyl)-3-{2-[ethyl(3-methylphenyl)amin...)
Affinity DataEC50:  20nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20468(3-(2-bromophenyl)-1-{2-[ethyl(3-methylphenyl)amino...)
Affinity DataEC50:  16nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20473(1-(3-bromophenyl)-3-{2-[ethyl(3-methylphenyl)amino...)
Affinity DataEC50:  40nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20474(1-(4-bromophenyl)-3-{2-[ethyl(3-methylphenyl)amino...)
Affinity DataEC50:  63nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20475(3-{2-[ethyl(3-methylphenyl)amino]ethyl}-1-naphthal...)
Affinity DataEC50:  79nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20476(1-(2,3-dichlorophenyl)-3-{2-[ethyl(3-methylphenyl)...)
Affinity DataEC50:  20nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20477(1-(2,5-dichlorophenyl)-3-{2-[ethyl(3-methylphenyl)...)
Affinity DataEC50:  25nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20478(1-(2-bromophenyl)-3-{2-[(3-methylphenyl)amino]ethy...)
Affinity DataEC50: >158nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20479(1-(2-bromophenyl)-3-{2-[methyl(3-methylphenyl)amin...)
Affinity DataEC50:  40nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20480(1-{2-[benzyl(3-methylphenyl)amino]ethyl}-3-(2-brom...)
Affinity DataEC50: >200nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20481(N-(2-{[(2-bromophenyl)carbamoyl]amino}ethyl)-N-(3-...)
Affinity DataEC50: >251nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20482(1-(2-bromophenyl)-3-{2-[ethyl(phenyl)amino]ethyl}u...)
Affinity DataEC50:  63nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20483(1-(2-bromophenyl)-3-{2-[ethyl(2-methylphenyl)amino...)
Affinity DataEC50:  126nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20484(1-(2-bromophenyl)-3-{2-[ethyl(4-methylphenyl)amino...)
Affinity DataEC50:  8nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20485(1-(2-bromophenyl)-3-{2-[ethyl(3-fluorophenyl)amino...)
Affinity DataEC50:  25nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20486(1-(2-bromophenyl)-3-{2-[(3,4-difluorophenyl)(ethyl...)
Affinity DataEC50:  16nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20487(1-(2-bromophenyl)-3-{2-[ethyl(3-fluoro-4-methylphe...)
Affinity DataEC50:  6nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20488((2E)-3-(4-chlorophenyl)-N-(3-methoxyphenyl)prop-2-...)
Affinity DataEC50:  20nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
LigandPNGBDBM20284(CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...)
Affinity DataEC50:  32nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
LigandPNGBDBM20489(1-(2-bromophenyl)-3-{2-[ethyl(methyl)(3-methylphen...)
Affinity DataEC50:  100nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20490(1-(2-bromophenyl)-3-[2-(2,3-dihydro-1H-indol-1-yl)...)
Affinity DataEC50:  158nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20491(1-(2-bromophenyl)-3-[2-(4-methyl-2,3-dihydro-1H-in...)
Affinity DataEC50:  40nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20492(1-(2-bromophenyl)-3-[2-(5-methyl-2,3-dihydro-1H-in...)
Affinity DataEC50:  50nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20493(1-(2-bromophenyl)-3-[2-(4-fluoro-2,3-dihydro-1H-in...)
Affinity DataEC50:  40nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20494(1-(2-bromophenyl)-3-[2-(5-fluoro-2,3-dihydro-1H-in...)
Affinity DataEC50:  79nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20495(3-(2-bromophenyl)-1-[2-(6-methyl-1,2,3,4-tetrahydr...)
Affinity DataEC50:  40nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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