TargetMu-type opioid receptor(Homo sapiens (Human))
Julius Maximilian University of W£Rzburg
Curated by ChEMBL
Julius Maximilian University of W£Rzburg
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]-Diprenorphine from human mu opioid receptor expressed in HEK293-TSA cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.661nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 140 min...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]UR-PI294 from human histamine H3 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing G-alphai2 and ...More data for this Ligand-Target Pair
Affinity DataKi: 2.09nMAssay Description:Displacement of [3H]mepyramine from human H1R expressed in Sf9 cells co-expressing RGS4 after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells incubated for 40 minsMore data for this Ligand-Target Pair
Affinity DataKi: 4.47nMAssay Description:Displacement of [3H]mepyramine from human H1R expressed in Sf9 cells co-expressing RGS4 after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Affinity DataKi: 4.90nMAssay Description:Displacement of [3H]histamine from human histamine 4 receptor expressed in HEK293T cell membranes incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]mepyramine from human H1R expressed in Sf9 cells co-expressing RGS4 after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Julius Maximilian University of W£Rzburg
Curated by ChEMBL
Julius Maximilian University of W£Rzburg
Curated by ChEMBL
Affinity DataKi: 5.60nMAssay Description:Displacement of [3H]-CP55950 from human CB2 receptor expressed in HEK cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
Affinity DataKi: 7.08nMAssay Description:Displacement of [3H]mepyramine from human H1R expressed in Sf9 cells co-expressing RGS4 after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 8.10nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Displacement of [3H]mepyramine from human histamine 1 receptor expressed in Sf9 cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Affinity DataKi: 8.5nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing G-alphai2 an...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in human SK-N-MC cell membrane incubated for 60 minsMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in human SK-N-MC cell membrane incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 14.8nMAssay Description:Displacement of [3H]mepyramine from human H1R expressed in Sf9 cells co-expressing RGS4 after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in human SK-N-MC cell membrane incubated for 60 minsMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Affinity DataKi: 18.6nMAssay Description:Displacement of [3H]histamine from human H4R expressed in Sf9 cells co-expressing RGS19, Galphai2 and Gbeta1gamma2 after 60 mins by liquid scintillat...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Julius Maximilian University of W£Rzburg
Curated by ChEMBL
Julius Maximilian University of W£Rzburg
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-CP55950 from human CB2 receptor expressed in HEK cell membranes after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in Sf9 cell membranes by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing G-alphai2 an...More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from human histamine H3 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing ...More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in Sf9 cell membranes by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 140 min...More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in Sf9 cell membranes by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Binding affinity to histamine 4 receptor (unknown origin)More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Julius Maximilian University of W£Rzburg
Curated by ChEMBL
Julius Maximilian University of W£Rzburg
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Displacement of [3H]-CP55950 from human CB2 receptor expressed in HEK cell membranes after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Displacement of [3H]histamine from human histamine 4 receptor expressed in Sf9 cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Affinity DataKi: 57.5nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 140 min...More data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in Sf9 cell membranes by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
Affinity DataKi: 66nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in Sf9 cell membranes by competitive binding assayMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
Curated by ChEMBL
Affinity DataKi: 69nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in sf9 cells co-expressing mammalian Galphai2 and Gbeta1gamma2More data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 140 min...More data for this Ligand-Target Pair