Affinity DataKi: 6.5nMAssay Description:In vitro Prostacyclin (PGI-2) receptor binding assay was determined based on displacement of [3H]-Iloprost radioligand from cloned human IP receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Ability to inhibit binding of [3H]iloprost to cloned human prostaglandin I2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 8.90nMAssay Description:Displacement of [3H]iloprost from human Prostanoid IP receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]iloprost from human Prostanoid IP receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Ability to inhibit binding of [3H]iloprost to cloned human prostaglandin I2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:In vitro Prostacyclin (PGI-2) receptor binding assay was determined based on displacement of [3H]-Iloprost radioligand from cloned human IP receptorMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of [3H]iloprost from human Prostanoid IP receptorMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Ability to inhibit binding of [3H]iloprost to cloned human prostaglandin I2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Displacement of [3H]iloprost from cloned human PGI2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:Displacement of [3H]iloprost from cloned human PGI2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Tested for inhibition of 3[H]-iloprost binding to human IP receptorMore data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Tested for inhibition of 3[H]-iloprost binding to human IP receptorMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [3H]iloprost from human Prostanoid IP receptorMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Displacement of [3H]iloprost from human Prostanoid IP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PGD-2 from human Prostanoid DP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]SQ-29,548 from human Prostanoid TP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PGF-2 from human Prostanoid FP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-PGE-2 from human Prostanoid EP2 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-PGE-2 from human Prostanoid EP2 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP1 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-PGE-2 from human Prostanoid EP2 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PGF-2 from human Prostanoid FP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-PGE-2 from human Prostanoid EP2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PGD-2 from human Prostanoid DP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]SQ-29,548 from human Prostanoid TP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 1.02E+3nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.90E+3nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Displacement of [3H]PGD-2 from human Prostanoid DP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 6.80E+3nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP3 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 8.20E+3nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP3 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 9.60E+3nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP1 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGF-2 from human Prostanoid FP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-PGE-2 from human Prostanoid EP2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SQ-29,548 from human Prostanoid TP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of [125I]-Cholecystokinin-8 (125I-CCK-8) binding to Cholecystokinin type A receptor of rat pancreatic membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.0870nMAssay Description:Compound was evaluated for the inhibition of 124 I-CCK-8 binding at Cholecystokinin type B receptor on guinea pig cerebral cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.0870nMAssay Description:Inhibition of [125I]-Cholecystokinin-8 binding to Cholecystokinin type B receptor of guinea pig cerebral cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMAssay Description:Tested for the inhibition of [125I]-PYY binding to HEK 293 cells stably expressed with human neuropeptide NPY Y5 receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.370nMAssay Description:Inhibition of [125I]-Cholecystokinin-8 binding to Cholecystokinin type B receptor of guinea pig cerebral cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.470nMAssay Description:Inhibition of [125I]-Cholecystokinin-8 binding to Cholecystokinin type B receptor of guinea pig cerebral cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:Inhibitory concentration of total specific binding of [125I]- -PYY to HEK 293 cells transfected with Human NPY-Y5 cDNA (compound prepared by manual s...More data for this Ligand-Target Pair