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Found 74 with Last Name = 'takemura' and Initial = 't'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430145(CHEMBL2338266)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109771(3-{4-[(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-...)
Affinity DataIC50:  3.5nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430135(CHEMBL2338251)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430139(CHEMBL2338247)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430136(CHEMBL2338250)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109757(CHEMBL355937 | {2-[(1-{2-[1-(Benzooxazole-2-carbon...)
Affinity DataIC50:  7.20nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109765(CHEMBL357495 | [4-(1-{2-[1-(Benzooxazole-2-carbony...)
Affinity DataIC50:  7.40nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109777(CHEMBL118176 | {4-[((R)-1-{(S)-2-[(S)-1-(Benzooxaz...)
Affinity DataIC50:  7.60nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430140(CHEMBL2338246)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430132(CHEMBL2338254)
Affinity DataIC50:  8nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430141(CHEMBL2338245)
Affinity DataIC50:  8nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430147(CHEMBL2338264)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109761(2,2-Dimethyl-propionic acid (S)-2-{2-[((S)-1-{(S)-...)
Affinity DataIC50:  8.90nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430147(CHEMBL2338264)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430134(CHEMBL2338252)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430142(CHEMBL2338244)
Affinity DataIC50:  10nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430138(CHEMBL2338248)
Affinity DataIC50:  11nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430137(CHEMBL2338249)
Affinity DataIC50:  11nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430148(CHEMBL2338263)
Affinity DataIC50:  12nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430148(CHEMBL2338263)
Affinity DataIC50:  12nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109763(4-Carboxymethoxy-benzoic acid (1-{2-[1-(benzooxazo...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430140(CHEMBL2338246)
Affinity DataIC50:  13nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430134(CHEMBL2338252)
Affinity DataIC50:  17nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430138(CHEMBL2338248)
Affinity DataIC50:  18nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430131(CHEMBL2338255)
Affinity DataIC50:  20nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430143(CHEMBL2338243)
Affinity DataIC50:  24nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430151(CHEMBL2338259)
Affinity DataIC50:  24nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430146(CHEMBL2338265)
Affinity DataIC50:  25nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430132(CHEMBL2338254)
Affinity DataIC50:  26nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430150(CHEMBL2338261)
Affinity DataIC50:  27nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430136(CHEMBL2338250)
Affinity DataIC50:  29nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430131(CHEMBL2338255)
Affinity DataIC50:  29nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430144(CHEMBL2338242)
Affinity DataIC50:  29nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430139(CHEMBL2338247)
Affinity DataIC50:  32nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109756((4-{[(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-p...)
Affinity DataIC50:  33nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430135(CHEMBL2338251)
Affinity DataIC50:  35nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430133(CHEMBL2338253)
Affinity DataIC50:  35nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430143(CHEMBL2338243)
Affinity DataIC50:  36nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430152(CHEMBL2338258)
Affinity DataIC50:  39nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430145(CHEMBL2338266)
Affinity DataIC50:  39nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430151(CHEMBL2338259)
Affinity DataIC50:  54nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430149(CHEMBL2338262)
Affinity DataIC50:  59nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109759(CHEMBL358686 | N-(1-{2-[1-(Benzooxazole-2-carbonyl...)
Affinity DataIC50:  66nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430146(CHEMBL2338265)
Affinity DataIC50:  72nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109775(3-(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-prop...)
Affinity DataIC50:  72nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430155(CHEMBL2338260)
Affinity DataIC50:  74nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430149(CHEMBL2338262)
Affinity DataIC50:  83nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430144(CHEMBL2338242)
Affinity DataIC50: >100nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430142(CHEMBL2338244)
Affinity DataIC50: >100nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430137(CHEMBL2338249)
Affinity DataIC50: >100nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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