Affinity DataKi: 0.00800nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Ability to inhibit [125I]ET1 binding to the Endothelin A receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0770nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]-PDBu from recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
Affinity DataKi: 0.910nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by PDSP Ki Database
Meiji Seika Kaisha
Curated by PDSP Ki Database
Affinity DataKi: 1nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I]-orexin-A from human OX2 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I]-orexin-A from human OX1 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I]-orexin-A from human OX2 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Binding inhibition constant was determined by inhibition of [125I]iodocyanopindolol binding to Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity at human CRF1 receptor (CRFR1) on HeLA cell membranes.More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by PDSP Ki Database
Meiji Seika Kaisha
Curated by PDSP Ki Database
Affinity DataKi: 2nMAssay Description:Displacement of [125I]-orexin-A from human OX2 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]-orexin-A from human OX2 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by PDSP Ki Database
Meiji Seika Kaisha
Curated by PDSP Ki Database
TargetGlutamate receptor ionotropic, kainate 1(RAT)
Suntory Institute For Bioorganic Research
Curated by PDSP Ki Database
Suntory Institute For Bioorganic Research
Curated by PDSP Ki Database
Affinity DataKi: 2.60nMAssay Description:Binding inhibition constant was determined by inhibition of [125I]iodocyanopindolol binding to Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [125I]-orexin-A from human OX1 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity at human CRF1 receptor (CRFR1) on HeLA cell membranes.More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-PDBu from recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 3.10nMAssay Description:Binding affinity at human CRF1 receptor (CRFR1) on HeLA cell membranes.More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Agonistic activity was determined by measuring cAMP accumulation in CHO cells expressing cloned human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding inhibition constant was determined by inhibition of [125I]-iodocyanopindolol binding to Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by PDSP Ki Database
Meiji Seika Kaisha
Curated by PDSP Ki Database
Affinity DataKi: 5nMAssay Description:Displacement of [125I]-orexin-A from human OX2 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 5.5nMAssay Description:Binding affinity at human CRF1 receptor (CRFR1) on HeLA cell membranes.More data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]-PDBu from recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of [125I]-orexin-A from human OX2 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]-Raclopride from human D2 receptor (unknown origin) expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Suntory Institute For Bioorganic Research
Curated by PDSP Ki Database
Suntory Institute For Bioorganic Research
Curated by PDSP Ki Database
Affinity DataKi: 9nMAssay Description:Displacement of [125I]-orexin-A from human OX1 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [125I]-orexin-A from human OX1 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Binding inhibition constant was determined by inhibition of [125I]-iodocyanopindolol binding to Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-PDBu from recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding inhibition constant was determined by inhibition of [125I]-iodocyanopindolol binding to Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-PDBu from recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding inhibition constant was determined by inhibition of [125I]iodocyanopindolol binding to Beta-2 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding inhibition constant was determined by inhibition of [125I]-iodocyanopindolol binding to Beta-2 adrenergic receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by PDSP Ki Database
Meiji Seika Kaisha
Curated by PDSP Ki Database
Affinity DataKi: 30nMAssay Description:Displacement of [125I]-orexin-A from human OX1 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Binding inhibition constant was determined by inhibition of [125I]-iodocyanopindolol binding to Beta-3 adrenergic receptorMore data for this Ligand-Target Pair