Affinity DataKi: 0.140nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPurchase
Affinity DataKi: 0.140nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.220nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of TGFBR1 in human whole blood assessed as apparent inhibition constant by measuring reduction in TGFbeta-induced SMAD phosphorylationMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Mus musculus)
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Inhibition of TGFBR1 in mouse whole blood assessed as apparent inhibition constant by measuring reduction in TGFbeta-induced SMAD phosphorylationMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 116nMAssay Description:Inhibition of His-tagged BTK (unknown origin) after 1.5 hrs by HTRF analysisMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 127nMAssay Description:Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 143nMAssay Description:Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 173nMAssay Description:Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.More data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 223nMAssay Description:Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.More data for this Ligand-Target Pair
Affinity DataKi: 270nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 324nMAssay Description:Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 341nMAssay Description:Inhibition of muscarinic acetylcholine receptor M1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 425nMAssay Description:Inhibition of His-tagged BTK (unknown origin) after 1.5 hrs by HTRF analysisMore data for this Ligand-Target Pair
Affinity DataKi: 430nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 480nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 485nMAssay Description:Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 492nMAssay Description:Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.More data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 597nMAssay Description:Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.More data for this Ligand-Target Pair