TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibition of human PACE4 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.75nMAssay Description:Inhibition of human PC1/3 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.810nMAssay Description:Inhibition of human furin by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human furin by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of human furin by fluorescence assayMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of human PC5/6 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of human PC1/3 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Inhibition of human PACE4 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of human PACE4 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of human furin by fluorescence assayMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Inhibition of human PC5/6 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Inhibition of human PC1/3 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Inhibition of human PC5/6 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 8.70nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 14nM ΔG°: -44.8kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Inhibition of human PACE4 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 44nM ΔG°: -42.0kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 50nM ΔG°: -41.7kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Inhibition of human furin by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Inhibition of human PC1/3 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 53nM ΔG°: -41.5kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Inhibition of human PC2 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 57nM ΔG°: -41.3kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 61nM ΔG°: -41.2kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 61nM ΔG°: -41.2kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Inhibition of human furin by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 65nM ΔG°: -41.0kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 67nMAssay Description:Inhibition of human PACE4 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of human PC1/3 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Inhibition of human furin by fluorescence assayMore data for this Ligand-Target Pair