TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: 0.600nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human c-Met kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant N-terminal histidine-tagged HDAC6 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged HDAC1 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: <10nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human RONMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human c-Met kinase domainMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: <10nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: <10nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: 10nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human RONMore data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: 12nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human c-MetMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human RONMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: 16nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Compound was tested for inhibitory activity against ThrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Compound was tested for inhibitory activity against ThrombinMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human RONMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human RONMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human RONMore data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: 25nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human RONMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human RONMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of RON phosphorylation in human PC3 cellsMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of RON phosphorylation in human HT29 cellsMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human RONMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Laboratoires Chemrf Inc/Chemrf Laboratories
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of human RONMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite De Montreal At Succursale Centre-Ville
Universite De Montreal At Succursale Centre-Ville
Affinity DataIC50: 39nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair