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Found 48 with Last Name = 'tsubaki' and Initial = 'k'
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50095202(4-[2-Hydroxy-3-((E)-3-hydroxy-4-methyl-oct-1-en-6-...)
Affinity DataKi:  80nMAssay Description:Tested for inhibition of 3[H]-iloprost binding to human IP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50095203(CHEMBL94751 | [(S)-6-(3-Benzhydryl-6-oxo-6H-pyrida...)
Affinity DataKi:  94nMAssay Description:Tested for inhibition of 3[H]-iloprost binding to human IP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha subunit B(Bos taurus (bovine))
Kyoto Prefectural University

LigandPNGBDBM33388(dehydroaltenusin derivative, 16)
Affinity DataIC50:  60nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha subunit B(Bos taurus (bovine))
Kyoto Prefectural University

LigandPNGBDBM33387(dehydroaltenusin derivative, 15)
Affinity DataIC50:  90nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha subunit B(Bos taurus (bovine))
Kyoto Prefectural University

LigandPNGBDBM33386(dehydroaltenusin derivative, 14)
Affinity DataIC50:  180nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha subunit B(Bos taurus (bovine))
Kyoto Prefectural University

LigandPNGBDBM33389(dehydroaltenusin derivative, 20)
Affinity DataIC50:  240nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha subunit B(Bos taurus (bovine))
Kyoto Prefectural University

LigandPNGBDBM33384(dehydroaltenusin)
Affinity DataIC50:  680nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha subunit B(Bos taurus (bovine))
Kyoto Prefectural University

LigandPNGBDBM33385(desmethyldehydroaltenusin, 2)
Affinity DataIC50:  890nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA tem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase eta(Homo sapiens (Human))
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase eta (amino acids 1 to 511) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA templ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase lambda(Homo sapiens (Human))
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of His-tagged human DNA polymerase lambda using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase iota(Mus musculus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of C-terminal His6-tagged mouse DNA polymerase iota using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of rat pol beta using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed DNA/RNA polymerase mu(Homo sapiens (Human))
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of His-tagged human DNA polymerase mu using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA tem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase eta(Homo sapiens (Human))
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase eta (amino acids 1 to 511) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA templ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA nucleotidylexotransferase(Bos taurus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of calf thymus TdT using oligo(dT)18 (3'-OH) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase iota(Mus musculus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of C-terminal His6-tagged mouse DNA polymerase iota using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase lambda(Homo sapiens (Human))
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of His-tagged human DNA polymerase lambda using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed DNA/RNA polymerase mu(Homo sapiens (Human))
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of His-tagged human DNA polymerase mu using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM33388(dehydroaltenusin derivative, 16)
Affinity DataIC50:  1.10E+4nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of rat pol beta using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA nucleotidylexotransferase(Bos taurus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50:  1.19E+4nMAssay Description:Inhibition of calf thymus TdT using oligo(dT)18 (3'-OH) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM33387(dehydroaltenusin derivative, 15)
Affinity DataIC50:  2.40E+4nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM33386(dehydroaltenusin derivative, 14)
Affinity DataIC50:  3.50E+4nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM33384(dehydroaltenusin)
Affinity DataIC50:  6.40E+4nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM33389(dehydroaltenusin derivative, 20)
Affinity DataIC50:  8.90E+4nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Mus musculus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse IMP dehydrogenase type 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Mus musculus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse IMP dehydrogenase type 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyribonuclease-1(Bos taurus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of bovine deoxyribonuclease I by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyribonuclease-1(Bos taurus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of bovine deoxyribonuclease I by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolynucleotide kinase(Enterobacteria phage T4)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of T4 polynucleotide kinase using 5'-hydroxyl termini of DNA and [gamma-32ATP] after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolynucleotide kinase(Enterobacteria phage T4)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of T4 polynucleotide kinase using 5'-hydroxyl termini of DNA and [gamma-32ATP] after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetT7 RNA polymerase(Enterobacteria phage T7)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of T7 RNA polymerase using salmon sperm DNA and [3H]UTP at 25 degree C after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetT7 RNA polymerase(Enterobacteria phage T7)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of T7 RNA polymerase using salmon sperm DNA and [3H]UTP at 25 degree C after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed DNA polymerase(Enterobacteria phage T4)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of T4 pol using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase I, thermostable(Thermus aquaticus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Taq polymerase using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate at 74 degree C after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase I, thermostable(Thermus aquaticus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Taq polymerase using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate at 74 degree C after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed DNA polymerase(Enterobacteria phage T4)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of T4 pol using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM33385(desmethyldehydroaltenusin, 2)
Affinity DataIC50:  1.26E+5nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha subunit B(Bos taurus (bovine))
Kyoto Prefectural University

LigandPNGBDBM33391(dehydroaltenusin derivative, 26)
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha subunit B(Bos taurus (bovine))
Kyoto Prefectural University

LigandPNGBDBM33392(dehydroaltenusin derivative, 31)
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha subunit B(Bos taurus (bovine))
Kyoto Prefectural University

LigandPNGBDBM33393(dehydroaltenusin derivative, 32)
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM33390(dehydroaltenusin derivative, 25)
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM33393(dehydroaltenusin derivative, 32)
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM33391(dehydroaltenusin derivative, 26)
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha subunit B(Bos taurus (bovine))
Kyoto Prefectural University

LigandPNGBDBM33390(dehydroaltenusin derivative, 25)
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM33392(dehydroaltenusin derivative, 31)
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed