Reaction Details Report a problem with these data
Target
Polynucleotide kinase
Ligand
BDBM50356642
Substrate
n/a
Meas. Tech.
ChEMBL_785421 (CHEMBL1919800)
IC50
>100000±n/a nM
Citation
 Maruo, S; Kuriyama, I; Kuramochi, K; Tsubaki, K; Yoshida, H; Mizushina, Y Inhibitory effect of novel 5-O-acyl juglones on mammalian DNA polymerase activity, cancer cell growth and inflammatory response. Bioorg Med Chem 19:5803-12 (2011) [PubMed]  Article 
Target
Name:
Polynucleotide kinase
Synonyms:
KIPN_BPT4 | pseT
Type:
PROTEIN
Mol. Mass.:
34626.48
Organism:
Enterobacteria phage T4
Description:
ChEMBL_1297302
Residue:
301
Sequence:
MKKIILTIGCPGSGKSTWAREFIAKNPGFYNINRDDYRQSIMAHEERDEYKYTKKKEGIVTGMQFDTAKSILYGGDSVKGVIISDTNLNPERRLAWETFAKEYGWKVEHKVFDVPWTELVKRNSKRGTKAVPIDVLRSMYKSMREYLGLPVYNGTPGKPKAVIFDVDGTLAKMNGRGPYDLEKCDTDVINPMVVELSKMYALMGYQIVVVSGRESGTKEDPTKYYRMTRKWVEDIAGVPLVMQCQREQGDTRKDDVVKEEIFWKHIAPHFDVKLAIDDRTQVVEMWRRIGVECWQVASGDF
  
Inhibitor
Name:
BDBM50356642
Synonyms:
CHEMBL1917196
Type:
Small organic molecule
Emp. Form.:
C22H28O4
Mol. Mass.:
356.4553
SMILES:
CCCCCCCCCCCC(=O)Oc1cccc2C(=O)C=CC(=O)c12 |c:21|
Structure:
Search PDB for entries with ligand similarity: