TargetD(2) dopamine receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 0.0890nMAssay Description:Displacement of [3H]Spiperone from human recombinant dopamine D2S receptor expressed in CHO cells after 2 hrsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Displacement of [125I]Peptide YY from neuropeptide Y receptor type 2 in human KAN-TS cells after 2 hrsMore data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]PAF from platelet activating factor receptor in human platelets after 3 hrsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Displacement of [125I]Peptide YY from neuropeptide Y receptor type 1 in human SK-N-MC cells after 60 minsMore data for this Ligand-Target Pair
TargetB1 bradykinin receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H](Des-Arg10)-Kallidin from bradykinin B1 receptor in human IMR90 cells after 60 minsMore data for this Ligand-Target Pair
TargetB2 bradykinin receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]Bradykinin from human recombinant bradykinin B2 receptor expressed in CHEM1 cells after 60 minsMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]Pyrilamine from human recombinant histamine H1 receptor expressed in CHOK1 cells after 3 hrsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]Dexamethasone from glucocorticoid receptor in human HeLaS3 cells after 2 hrsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]GR65630 from human recombinant 5HT3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]Substance P from human recombinant substance P receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]CGP54626 from human recombinant GABAB1A receptor expressed in CHO cells after 3 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]Mibolerone from rat recombinant androgen receptor expressed in Escherichia coli after 4 hrsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 8.80nMAssay Description:Displacement of [3H]Haloperidol from sigma 1 receptor in human jurkat cells after 4 hrsMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [125I]Aminopotentidine from human recombinant histamine H2 receptor expressed in CHOK1 cells after 2 hrsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Displacement of [125I]Peptide YY from neuropeptide Y receptor type 2 in human KAN-TS cells after 2 hrsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 0.220nMAssay Description:Displacement of [125I]Peptide YY from neuropeptide Y receptor type 1 in human SK-N-MC cells after 60 minsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Displacement of [3H]Spiperone from human recombinant dopamine D2S receptor expressed in CHO cells after 2 hrsMore data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Displacement of [3H]PAF from platelet activating factor receptor in human platelets after 3 hrsMore data for this Ligand-Target Pair
TargetB1 bradykinin receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 0.870nMAssay Description:Displacement of [3H](Des-Arg10)-Kallidin from bradykinin B1 receptor in human IMR90 cells after 60 minsMore data for this Ligand-Target Pair
TargetB2 bradykinin receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]Bradykinin from human recombinant bradykinin B2 receptor expressed in CHEM1 cells after 60 minsMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Displacement of [3H]Pyrilamine from human recombinant histamine H1 receptor expressed in CHOK1 cells after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Displacement of [3H]Substance P from human recombinant substance P receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Displacement of [3H]Dexamethasone from glucocorticoid receptor in human HeLaS3 cells after 2 hrsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Displacement of [3H]CGP54626 from human recombinant GABAB1A receptor expressed in CHO cells after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Displacement of [3H]Mibolerone from rat recombinant androgen receptor expressed in Escherichia coli after 4 hrsMore data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 10nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 10nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 10nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]GR65630 from human recombinant 5HT3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 20nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]Haloperidol from sigma 1 receptor in human jurkat cells after 4 hrsMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]Aminopotentidine from human recombinant histamine H2 receptor expressed in CHOK1 cells after 2 hrsMore data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 40nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 60nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 70nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 110nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 130nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 130nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 130nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 140nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 180nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 180nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 210nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 250nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 250nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 250nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 260nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of SFLLRN-NH2-stimulated PAR1-mediated platelet activation in platelet-rich human plasma assessed as surface expression of P-selectin afte...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 270nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States
The Broad Institute , Cambridge, Massachusetts 02142, United States
Affinity DataIC50: 290nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair