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Found 572 with Last Name = 'wadood' and Initial = 'a'
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM175363(Ethyl 2-hydrazinyl-1,4-dimethyl-6-(p-nitrophenyl)-...)
Affinity DataKi:  1.46E+4nM IC50:  1.50E+4nMAssay Description:Reaction mixture consisting of 25 無 of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 無 of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM175361(Methyl 2-hydrazinyl-1,4-dimethyl-6-(p-tolyl)-1,6-d...)
Affinity DataKi:  1.51E+4nM IC50:  1.78E+4nMAssay Description:Reaction mixture consisting of 25 無 of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 無 of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM175362(Ethyl 2-hydrazinyl-6-(3-hydroxyphenyl)-1,4-dimethy...)
Affinity DataKi:  1.53E+4nM IC50:  1.74E+4nMAssay Description:Reaction mixture consisting of 25 無 of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 無 of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM175352(Ethyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydr...)
Affinity DataKi:  1.58E+4nM IC50:  3.56E+4nMAssay Description:Reaction mixture consisting of 25 無 of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 無 of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM175353(Ethyl 6-methyl-4-(p-tolyl)-2-thioxo-1,2,3,4-tetrah...)
Affinity DataKi:  1.60E+4nM IC50:  4.29E+4nMAssay Description:Reaction mixture consisting of 25 無 of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 無 of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM175358(Ethyl 2-hydrazinyl-1,4-dimethyl-6-phenyl-1,6-dihyd...)
Affinity DataKi:  1.76E+4nM IC50:  2.08E+4nMAssay Description:Reaction mixture consisting of 25 無 of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 無 of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM175357(Ethyl 6-methyl-4-(p-nitrophenyl)-2-thioxo-1,2,3,4-...)
Affinity DataKi:  1.94E+4nM IC50:  4.05E+4nMAssay Description:Reaction mixture consisting of 25 無 of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 無 of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM175360(Methyl 2-hydrazinyl-1,4-dimethyl-6-phenyl-1,6-dihy...)
Affinity DataKi:  1.99E+4nM IC50:  2.36E+4nMAssay Description:Reaction mixture consisting of 25 無 of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 無 of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM50229993(2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...)
Affinity DataKi:  2.00E+4nM IC50:  2.10E+4nMAssay Description:Reaction mixture consisting of 25 無 of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 無 of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM175355(Methyl 6-methyl-4-(p-tolyl)-2-thioxo-1,2,3,4-tetra...)
Affinity DataKi:  2.20E+4nM IC50:  4.13E+4nMAssay Description:Reaction mixture consisting of 25 無 of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 無 of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM175354(Methyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahyd...)
Affinity DataKi:  2.28E+4nM IC50:  3.60E+4nMAssay Description:Reaction mixture consisting of 25 無 of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 無 of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM175356(Ethyl 4-(3-hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,...)
Affinity DataKi:  2.57E+4nM IC50:  3.47E+4nMAssay Description:Reaction mixture consisting of 25 無 of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 無 of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM175359(Ethyl 2-hydrazinyl-1,4-dimethyl-6-(p-tolyl)-1,6-di...)
Affinity DataKi:  2.94E+4nM IC50:  2.60E+4nMAssay Description:Reaction mixture consisting of 25 無 of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 無 of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Hazara University

LigandPNGBDBM11023((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50:  40nMpH: 7.7Assay Description:Total volume of the reaction mixture was 100 無 containing 60 無, Na2HPO4 buffer, 50 mM and pH 7.7. Ten 無 test compound 0.5 mM well-1 was added foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193719(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(2-fluoro...)
Affinity DataIC50:  100nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193733(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(3,4-dich...)
Affinity DataIC50:  120nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
Universiti Teknologi Mara (Uitm), Puncak Alam Campus

LigandPNGBDBM60585(2-(3'-Fluorophenyl)-7-methyl-1H-benzo[d]imidazole ...)
Affinity DataIC50:  165nMAssay Description:The 135 無 of 50 mM phosphate saline buffer pH (6.8), solution of enzyme (20 無), and 20 無 of test sample with 70% DMSO was added to 96-well plate. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193734(2-(4-(di(1H-indol-3-yl)methyl)benzoyl)-N-(4(triflu...)
Affinity DataIC50:  200nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM50129797(CHEMBL3629072)
Affinity DataIC50:  400nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193720(N-(2-Chlorophenyl)-2-(4-(di(1H-indol-3-yl)methyl)b...)
Affinity DataIC50:  500nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50019283(CHEMBL3289121)
Affinity DataIC50:  700nMAssay Description:Compound was tested for TXA2 receptor antagonism by measuring its ability to inhibit contraction of rat aorta induced by the stable TXA2 agonist U-46...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM50129738(CHEMBL3629545)
Affinity DataIC50:  700nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Hazara University

LigandPNGBDBM11023((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50:  850nMpH: 7.7Assay Description:Total volume of the reaction mixture was 100 無. It contained 60 無 Na2HPO4 buffer with concentration of 50 mM and pH 7.7. 10 無 test compound (0.5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM50510735(CHEMBL4567565)
Affinity DataIC50:  960nMAssay Description:Inhibition of human beta-glucuronidase pre-incubated for 30 mins before p-nitrophenyl-beta-D-glucuronide substrate addition by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50019166(CHEMBL336718)
Affinity DataIC50:  1.10E+3nMAssay Description:Compound was tested for TXA2 receptor antagonism by measuring its ability to inhibit contraction of rat aorta induced by the stable TXA2 agonist U-46...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM50129802(CHEMBL3629548)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50233861(CHEMBL4084524)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM50129798(CHEMBL3629071)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM50510743(CHEMBL4462023)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human beta-glucuronidase pre-incubated for 30 mins before p-nitrophenyl-beta-D-glucuronide substrate addition by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM181084(2-(4-(benzo[d]thiazol-2-yl)benzoyl)-N-(4-nitrophen...)
Affinity DataIC50:  1.40E+3nMpH: 6.8 T: 2°CAssay Description:To understand the binding modes of the compounds given in Table 1, all ligands were docked into the binding site of Urease enzyme. The top ranked con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM50129744(CHEMBL3629078)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM50129746(CHEMBL3629076)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM50129801(CHEMBL3629549)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50277802(CHEMBL4172107)
Affinity DataIC50:  1.60E+3nMAssay Description:Antagonistic activity for inhibition of histamine H2 receptor from anesthetized ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM60592(2-(4-(benzo[d]thiazol-2-yl)benzoyl)-N-(4-(trifluor...)
Affinity DataIC50:  1.60E+3nMpH: 6.8 T: 2°CAssay Description:To understand the binding modes of the compounds given in Table 1, all ligands were docked into the binding site of Urease enzyme. The top ranked con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50008884(CHEMBL3237329)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM50129804(CHEMBL3629546)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease subunit alpha(Bacillus pasteurii)
Hazara University

LigandPNGBDBM173607((Z)-2-((Z)-(Napthalen-1-ylmethylene)hydrazono)thia...)
Affinity DataIC50:  1.73E+3nMpH: 7.0Assay Description:This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50019285(CHEMBL3289122)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50008901(CHEMBL2430239)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable maltase-glucoamylase 2(Homo sapiens)
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable maltase-glucoamylase 2(Homo sapiens)
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50528910(CHEMBL4472850)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50277979(CHEMBL4167683)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM181090(2-(4-(benzo[d]thiazol-2-yl)benzoyl)-N-(3,4-dichlor...)
Affinity DataIC50:  2.10E+3nMpH: 6.8 T: 2°CAssay Description:To understand the binding modes of the compounds given in Table 1, all ligands were docked into the binding site of Urease enzyme. The top ranked con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50233856(CHEMBL4092265)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM50092444(CHEMBL3586121)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of beta-D-glucuronidase (unknown origin) assessed as reduction in p-nitrophenol formation using p-nitrophenyl-beta-D-glucuronide substarte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50092444(CHEMBL3586121)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50160569(CHEMBL3785671)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Hazara University

LigandPNGBDBM152497((E)-N'-(6-Bromo-2-oxoindolin-3-ylidene)-2-(2,4...)
Affinity DataIC50:  2.20E+3nMAssay Description:10 無 of test samples (5 mg/mL DMSO solution) were reconstituted in 100 無 of 100 mM-phosphate buffer (pH6.8) in 96-well microplate and incubated wit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM193670(N,N'-(disulfanediylbis(2,1-phenylene))bis(2,4,...)
Affinity DataIC50:  2.20E+3nMAssay Description:β-glucuronidase activity was determined by measuring absorbance at 405 nm of p-nitrophenol formed substrate by spectrophotometric method. 250 無...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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