Affinity DataKi: 2nMAssay Description:Displacement of [3H]estradiol from human ERalpha ligand binding domain expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Institute Of Molecular Physiology
Curated by ChEMBL
Institute Of Molecular Physiology
Curated by ChEMBL
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of 5-LOXMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Institute Of Molecular Physiology
Curated by ChEMBL
Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Institute Of Molecular Physiology
Curated by ChEMBL
Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 5-LOXMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of LOX5 in human whole blood assessed as inhibition of conversion of aracidonic acid to leukotrineMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of rat recombinant GGTase-1 by SDS-PAGE end point assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Institute Of Molecular Physiology
Curated by ChEMBL
Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK2/Cyclin EMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Institute Of Molecular Physiology
Curated by ChEMBL
Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK2/Cyclin BMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of 5-LOXMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of LOX5 in human whole blood assessed as inhibition of conversion of aracidonic acid to leukotrineMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of rat recombinant GGTase-1 by SDS-PAGE end point assayMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of rat recombinant GGTase-1 by SDS-PAGE end point assayMore data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of His-tagged Cdc25A expressed in the Escherichia coli BL21(DE3) using p-nitrophenyl phosphate as substrate for 80 mins by spectrophotomet...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Institute Of Molecular Physiology
Curated by ChEMBL
Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of ERK1/MAPKMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of rat recombinant GGTase-1 by SDS-PAGE end point assayMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of rat recombinant GGTase-1 by SDS-PAGE end point assayMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat recombinant GGTase-1 by SDS-PAGE end point assayMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Rattus norvegicus)
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat recombinant GGTase-1 by SDS-PAGE end point assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+5nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Institut FüR Molekulare Physiologie
Curated by ChEMBL
Institut FüR Molekulare Physiologie
Curated by ChEMBL
Affinity DataEC50: 4.60E+3nMAssay Description:Binding affinity to human ERbeta ligand binding domain expressed in Escherichia coli BL21(DE3) cells assessed as recruitment of fluorescently labeled...More data for this Ligand-Target Pair
Affinity DataEC50: 275nMAssay Description:Binding affinity to human ERalpha ligand binding domain expressed in Escherichia coli BL21(DE3) cells assessed as recruitment of fluorescently labele...More data for this Ligand-Target Pair