Compile Data Set for Download or QSAR
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Found 131 with Last Name = 'wild' and Initial = 'h'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095409(5-tert-Butyl-3-[3-(2,3-dichloro-phenyl)-ureido]-1H...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50358043(CHEMBL1794051 | GW-5074)
Affinity DataIC50:  9nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095390(5-tert-Butyl-3-(3-naphthalen-1-yl-ureido)-1H-pyrro...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095392(5-tert-Butyl-3-[3-(3-chloro-phenyl)-ureido]-1H-pyr...)
Affinity DataIC50:  27nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095415(5-tert-Butyl-3-(3-naphthalen-1-yl-ureido)-1H-pyrro...)
Affinity DataIC50:  28nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095402(5-tert-Butyl-3-(3-p-tolyl-ureido)-furan-2-carboxyl...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095429(5-tert-Butyl-3-[3-(2,3-dichloro-phenyl)-ureido]-fu...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095428(5-tert-Butyl-3-(3-p-tolyl-ureido)-1H-pyrrole-2-car...)
Affinity DataIC50:  33nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095403(1-(5-tert-butyl-2-(methylcarbamoyl)thiophen-3-yl)-...)
Affinity DataIC50:  34nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095398(5-tert-Butyl-3-[3-(4-fluoro-phenyl)-ureido]-1H-pyr...)
Affinity DataIC50:  42nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095407(5-tert-Butyl-3-[3-(4-chloro-phenyl)-ureido]-1H-pyr...)
Affinity DataIC50:  43nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095397(5-tert-Butyl-3-[3-(2,3-dichloro-phenyl)-ureido]-1H...)
Affinity DataIC50:  44nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095426(5-tert-Butyl-3-(3-phenyl-ureido)-1H-pyrrole-2-carb...)
Affinity DataIC50:  44nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118338(US8653111, 62)
Affinity DataIC50:  50nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095401(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  56nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095412(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  57nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095424(5-tert-Butyl-3-[3-(2-chloro-phenyl)-ureido]-1H-pyr...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095408(5-tert-Butyl-3-(3-p-tolyl-ureido)-1H-pyrrole-2-car...)
Affinity DataIC50:  67nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095396(5-tert-Butyl-3-(3-p-tolyl-ureido)-furan-2-carboxyl...)
Affinity DataIC50:  73nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095391(5-tert-Butyl-3-[3-(4-fluoro-phenyl)-ureido]-thioph...)
Affinity DataIC50:  88nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095422(5-tert-Butyl-3-[3-(4-ethyl-phenyl)-ureido]-thiophe...)
Affinity DataIC50:  119nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095406(5-tert-Butyl-3-[3-(2,3-dichloro-phenyl)-ureido]-th...)
Affinity DataIC50:  180nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3527(US8524699, 18)
Affinity DataIC50:  180nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171824(US9085572, 34)
Affinity DataIC50:  180nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118341(US8653111, 85)
Affinity DataIC50:  190nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095418(5-tert-Butyl-3-[3-(4-fluoro-phenyl)-ureido]-furan-...)
Affinity DataIC50:  210nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095420(5-tert-Butyl-3-[3-(4-chloro-phenyl)-ureido]-thioph...)
Affinity DataIC50:  220nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095399(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  248nMAssay Description:Inhibition of p38 alpha2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095400(5-tert-Butyl-1-methyl-3-(3-naphthalen-1-yl-ureido)...)
Affinity DataIC50:  253nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109268(US8609698, 10)
Affinity DataIC50:  260nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095421(5-tert-Butyl-3-[3-(4-isopropyl-phenyl)-ureido]-thi...)
Affinity DataIC50:  270nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095423(5-tert-Butyl-3-(3-phenyl-ureido)-thiophene-2-carbo...)
Affinity DataIC50:  290nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095423(5-tert-Butyl-3-(3-phenyl-ureido)-thiophene-2-carbo...)
Affinity DataIC50:  290nMAssay Description:Inhibition of Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118328(US8653111, 7)
Affinity DataIC50:  340nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118344(US8653111, 103)
Affinity DataIC50:  350nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118346(US8653111, 129)
Affinity DataIC50:  360nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105619(1-(5-tert-Butyl-isoxazol-3-yl)-3-(4-phenoxy-phenyl...)
Affinity DataIC50:  360nMAssay Description:Inhibition of Escherichia coli derived Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095427(5-tert-Butyl-3-[3-(2,3-dichloro-phenyl)-ureido]-1-...)
Affinity DataIC50:  387nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095430(5-tert-Butyl-1-methyl-3-(3-p-tolyl-ureido)-1H-pyrr...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095399(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  413nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171821(US9085572, 6)
Affinity DataIC50:  430nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095405(5-Amino-3-(3-p-tolyl-ureido)-thiophene-2-carboxyli...)
Affinity DataIC50:  441nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095419(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  464nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3543(US8524699, 16)
Affinity DataIC50:  480nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095404(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  482nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118339(US8653111, 72)
Affinity DataIC50:  490nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118329(US8653111, 10)
Affinity DataIC50:  500nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105619(1-(5-tert-Butyl-isoxazol-3-yl)-3-(4-phenoxy-phenyl...)
Affinity DataIC50:  540nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118331(US8653111, 17)
Affinity DataIC50:  560nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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