TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 119nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 180nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 248nMAssay Description:Inhibition of p38 alpha2 kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 253nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of Escherichia coli derived Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 387nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 413nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 430nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 441nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 464nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
Affinity DataIC50: 480nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 482nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair