Affinity DataKi: 0.0800nM ΔG°: -57.1kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 0.110nM ΔG°: -56.3kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 0.148nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from rat histamine H3 receptor expressed in HEK293 cells after 45 mins by liquid scintillation spectromet...More data for this Ligand-Target Pair
Affinity DataKi: 0.190nM ΔG°: -54.9kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.363nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -52.6kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 0.501nM ΔG°: -52.5kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -52.1kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.676nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from rat histamine H3 receptor expressed in HEK293 cells after 45 mins by liquid scintillation spectromet...More data for this Ligand-Target Pair
Affinity DataKi: 0.790nM ΔG°: -51.4kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 0.790nM ΔG°: -51.4kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.832nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.950nM ΔG°: -51.0kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from rat histamine H3 receptor expressed in HEK293 cells after 45 mins by liquid scintillation spectromet...More data for this Ligand-Target Pair
Affinity DataKi: 1.58nM ΔG°: -49.7kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nM ΔG°: -49.7kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nM ΔG°: -49.3kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nM ΔG°: -48.8kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 2.51nM ΔG°: -48.6kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 2.51nM ΔG°: -48.6kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 2.51nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 2.51nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nM ΔG°: -48.5kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding affinity for 5-hydroxytryptamine 1F receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair