Found 1262 with Last Name = 'yadav' and Initial = 'd' 
Affinity DataKi: 0.0170nMAssay Description:Inhibition of recombinant BACE1 expressed in Escherichia coli using Arg- Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dabcyl)-Arg as substrate by f...More data for this Ligand-Target Pair
Affinity DataKi: 0.0360nMAssay Description:Inhibition of recombinant BACE1 expressed in Escherichia coli using Arg- Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dabcyl)-Arg as substrate by f...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of recombinant BACE1 expressed in Escherichia coli using Arg- Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dabcyl)-Arg as substrate by f...More data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Inhibition of recombinant BACE1 expressed in Escherichia coli using Arg- Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dabcyl)-Arg as substrate by f...More data for this Ligand-Target Pair
3D Structure (crystal)TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by PDSP Ki Database
Schering-Plough Research Institute
Curated by PDSP Ki Database
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by PDSP Ki Database
Schering-Plough Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 7.20nMAssay Description:Inhibition of recombinant BACE1 expressed in Escherichia coli using Arg- Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dabcyl)-Arg as substrate by f...More data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Inhibition of recombinant BACE1 expressed in Escherichia coli using Arg- Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dabcyl)-Arg as substrate by f...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of recombinant BACE2More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of recombinant BACE1 expressed in Escherichia coli using Arg- Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dabcyl)-Arg as substrate by f...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of recombinant BACE1 expressed in Escherichia coli using Arg- Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dabcyl)-Arg as substrate by f...More data for this Ligand-Target Pair
Affinity DataKi: 99nMAssay Description:Inhibition of recombinant BACE1 expressed in Escherichia coli using Arg- Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dabcyl)-Arg as substrate by f...More data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Inhibition of recombinant BACE2More data for this Ligand-Target Pair
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by PDSP Ki Database
Schering-Plough Research Institute
Curated by PDSP Ki Database
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by PDSP Ki Database
Schering-Plough Research Institute
Curated by PDSP Ki Database
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by PDSP Ki Database
Schering-Plough Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 530nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by PDSP Ki Database
Schering-Plough Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 690nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of recombinant BACE1 expressed in Escherichia coli using Arg- Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dabcyl)-Arg as substrate by f...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of recombinant BACE1 expressed in Escherichia coli using Arg- Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dabcyl)-Arg as substrate by f...More data for this Ligand-Target Pair
Affinity DataKi: 1.45E+3nMAssay Description:Inhibition of recombinant BACE2More data for this Ligand-Target Pair
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by PDSP Ki Database
Schering-Plough Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Affinity DataKi: 4.30E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Affinity DataKi: 7.10E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Affinity DataKi: 8.26E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by PDSP Ki Database
Schering-Plough Research Institute
Curated by PDSP Ki Database
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 2.50E+4nM IC50: 6.27E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 3.00E+4nM IC50: 7.00E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 3.40E+4nM IC50: 8.70E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 4.80E+4nM IC50: 6.70E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 4.80E+4nM IC50: 6.90E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 4.80E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 4.80E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 5.60E+4nM IC50: 9.10E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 6.30E+4nM IC50: 8.80E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 6.30E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 1.35E+5nM IC50: 1.65E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 1.35E+5nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 1.50E+5nM IC50: 2.75E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 1.50E+5nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 1.70E+5nM IC50: 4.85E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Central Drug Research Institute
Affinity DataKi: 1.70E+5nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 0.150nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2), 1 Mg...More data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 0.570nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BACE1 in human neuroblastoma cellsMore data for this Ligand-Target Pair
