Affinity DataKi: 180nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 5.85E+3nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 0.877nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
Affinity DataIC50: 1.22nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
Affinity DataIC50: 1.62nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 1.82nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 2.19nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition OF SGLT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
Affinity DataIC50: 2.42nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 2.82nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human SGLT2 expressed i HEK293 cell membranes assessed as reduction in [14C]-alpha-methyl glucopyranoside uptake incubated for 4 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 3.48nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 3.98nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 4.21nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.51nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 6.53nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 6.72nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 7.24nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
Affinity DataIC50: 7.83nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.17nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 8.64nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 12.3nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 13.7nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of gamma-secretase (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 17nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hamdard University
Curated by ChEMBL
Hamdard University
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:The COX activity was assayed colorimetrically by monitoring the appearance of oxidized N,N,N',N'-tetramethyl-pphenylenediamine (TMPD) at 590 ...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of amyloid beta 40 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
Ligand Info