Affinity DataKi: 0.140nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
Affinity DataKi: 0.560nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.960nMAssay Description:Competitive inhibition of human Glyoxalase-1 using GSH and MGO as substrate by Michaelis-Menten analysisMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of FAM-Bid binding to human BCL2 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Competitive inhibition of human Glyoxalase-1 using GSH and MGO as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of human Glyoxalase-1 using GSH and MGO as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Inhibition of FAM-Bid binding to human BCL2 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human erythrocyte Glyoxalase-1 using GSH and MGO as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Competitive inhibition of human Glyoxalase-1 using GSH and MGO as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 7.10nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human Glyoxalase-1More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human erythrocyte Glyoxalase-1More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 15.5nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 17.3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Competitive inhibition of human Glyoxalase-1 using GSH and MGO as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 21.5nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair