Affinity DataKi: 0.0800nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]citalopram from human SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]citalopram from human SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 0.760nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 0.950nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 0.950nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1.02nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1.04nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1.21nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1.32nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1.35nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1.78nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1.86nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1.98nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 2.06nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.25nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.26nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Indiana University
Curated by ChEMBL
Indiana University
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) cells using p-nitrophenyl phosphate as substrate after 2 to 3 mins by spectrophotometric...More data for this Ligand-Target Pair
Affinity DataKi: 2.94nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 2.94nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 3.14nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.45nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 3.68nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.16nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.54nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 4.67nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 4.84nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 4.88nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.63nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 5.87nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.42nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.77nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Displacement of [125I]IMPY from beta amyloid in human AD cortical tissueMore data for this Ligand-Target Pair
Affinity DataKi: 8.48nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.04nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.69nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10.1nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10.3nMAssay Description:Displacement of [125I]IMPY from beta amyloid in human AD cortical tissueMore data for this Ligand-Target Pair
Affinity DataKi: 11.5nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12.3nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 12.5nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair