TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Reversible mixed-type inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Competitive inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 mins...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Binding affinity to FLT3 (unknown origin)More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Binding affinity to wild type BCR-ABL (unknown origin)More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Binding affinity to wild type BCR-ABL T315I mutant (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Inhibition of recombinant wild type Abl (unknown origin) in presence of [33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Binding affinity to human recombinant His-tagged full length ABL1 expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 0.540nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 0.540nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 0.610nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 0.720nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 0.760nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 0.770nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 0.770nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 0.790nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of wild type Abl (unknown origin)More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of wild type BCR-ABL phosphorylation in mouse BaF3 cells incubated for 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of BCR-ABL phosphorylation in human K562 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of BCR-ABL (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant PDGFRalpha (unknown origin) in presence of [33P]-ATP by kinase hotspot assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BCR-ABL (unknown origin)More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BCR-ABL phosphorylation in human K562 cells incubated for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of BCR-ABL (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human DPP4 after 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) in presence of [33P]-ATP by kinase hotspot assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant Abl-T315I mutant (unknown origin) in presence of [33P]-ATP by kinase hotspot assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) in presence of [33P]-ATP by kinase hotspot assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 2.34nMAssay Description:Inhibition of human DPP4 after 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 2.64nMAssay Description:Inhibition of human DPP4 after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human DPP4 after 10 minsMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Abl T315I mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Abl T315I mutant (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Abl T315I mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of wild type Abl (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant SRC (unknown origin) in presence of [33P]-ATP by kinase hotspot assayMore data for this Ligand-Target Pair