Found 493 with Last Name = 'zhao' and Initial = 'xz' TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to myc-tagged human Plk1 PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence polarization as...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to myc-tagged full-length human Plk1 expressed in HEK-293T cells incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to myc-tagged human Plk1 PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence polarization as...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to myc-tagged human Plk1 PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence polarization as...More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 9.70nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to myc-tagged human Plk1 PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence polarization as...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to myc-tagged human Plk1 PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence polarization as...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of HIV-1 integrase-mediated strand transfer activity using [32P]-labeled oligonucleotide as substrate after 2 hrs by densitometric analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of HIV-1 integrase-mediated strand transfer activity using [32P]-labeled oligonucleotide as substrate after 2 hrs by densitometric analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to human N-terminal myc-tagged PLK1 polo-box domain (365 to 653 residues) expressed in HEK293T cells...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of HIV-1 integrase-mediated strand transfer activity using [32P]-labeled oligonucleotide as substrate after 2 hrs by densitometric analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to human full length N-terminal myc-tagged PLK1 expressed in HEK293T cells after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of HIV-1 integrase-mediated strand transfer activity using [32P]-labeled oligonucleotide as substrate after 2 hrs by densitometric analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of HIV-1 integrase-mediated strand transfer activity using [32P]-labeled oligonucleotide as substrate after 2 hrs by densitometric analysi...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to human full length N-terminal myc-tagged PLK1 expressed in HEK293T cells after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity using [32P]-labeled oligonucleotide a substrate after 30 mins by electrophoretic an...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to human full length N-terminal myc-tagged PLK1 expressed in HEK293T cells after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity using [32P]-labeled oligonucleotide a substrate after 30 mins by electrophoretic an...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of HIV-1 integrase-mediated strand transfer activity using [32P]-labeled oligonucleotide as substrate after 2 hrs by densitometric analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity using [32P]-labeled oligonucleotide a substrate after 30 mins by electrophoretic an...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to human full length N-terminal myc-tagged PLK1 expressed in HEK293T cells after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity expressed in Escherichia coli after 60 mins using [32P]-labeled oligonucleotide as ...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
National Institutes of Health
National Institutes of Health
Affinity DataIC50: 67nMAssay Description:The compound were evaluated in biochemical IN (integrase) assay that measure inhibitory potency (IC50 values)against both the 3'-processing(3'...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity expressed in Escherichia coli after 30 mins using [32P]-labeled oligonucleotide as ...More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity expressed in Escherichia coli after 60 mins using [32P]-labeled oligonucleotide as ...More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity using [32P]-labeled oligonucleotide a substrate after 30 mins by electrophoretic an...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of strand transfer activity of HIV-1 integrase using [gamma-32P]-labeled DNA as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to human N-terminal myc-tagged PLK1 polo-box domain (365 to 653 residues) expressed in HEK293T cells...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to human N-terminal myc-tagged PLK1 polo-box domain (365 to 653 residues) expressed in HEK293T cells...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity using [32P]-labeled oligonucleotide a substrate after 30 mins by electrophoretic an...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 119nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to human N-terminal myc-tagged PLK1 polo-box domain (365 to 653 residues) expressed in HEK293T cells...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
