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Found 98 with Last Name = 'ziereis' and Initial = 'k'
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50004677(Acetic acid 4-acetoxy-6-chloro-2,3-dimethoxy-napht...)
Affinity DataIC50:  500nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041799(1,8-Dihydroxy-2-[3-(3,4,5-trihydroxy-phenyl)-propy...)
Affinity DataIC50:  600nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041780(2-(2,5-Dihydroxy-benzyl)-1,8-dihydroxy-10H-anthrac...)
Affinity DataIC50:  900nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041782(3-(2,5-Dihydroxy-benzyl)-1,8-dihydroxy-10H-anthrac...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041803(4-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060860(9(10H)-anthracenone | 9,10-dihydro-9-oxoanthracene...)
Affinity DataIC50:  2.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060871(4-Hydroxy-5-methoxy-10H-anthracen-9-one | CHEMBL12...)
Affinity DataIC50:  2.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041774(1,8-Dihydroxy-2-[3-(4-hydroxy-phenyl)-propyl]-10H-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041806(3-(3,4-Dihydroxy-benzyl)-1,8-dihydroxy-10H-anthrac...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060898(5,8-Dihydroxy-[1,4]naphthoquinone | 5,8-dihydroxy-...)
Affinity DataIC50:  3.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060855(4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracene-2-car...)
Affinity DataIC50:  3.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041776(2-(3,4-Dihydroxy-benzyl)-1,8-dihydroxy-10H-anthrac...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060881(10-Benzoyl-1,8-dihydroxy-10H-anthracen-9-one | CHE...)
Affinity DataIC50:  4.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060891(1,2-Dihydroxy-10H-anthracen-9-one | CHEMBL123692)
Affinity DataIC50:  4.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060858(4,5-Dihydroxy-10H-anthracen-9-one | CHEMBL124951)
Affinity DataIC50:  4.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataIC50:  4.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060872(3,4-Dihydroxy-10H-anthracen-9-one | CHEMBL121693)
Affinity DataIC50:  4.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041778(2-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060867(1,8-Dichloro-10H-anthracen-9-one | CHEMBL122022)
Affinity DataIC50:  4.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041784(2-(2,4-Dihydroxy-benzyl)-1,8-dihydroxy-10H-anthrac...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041783(1,8-Dihydroxy-2-(2-hydroxy-benzyl)-10H-anthracen-9...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060884(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracene-2-carb...)
Affinity DataIC50:  6.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060895(Acetic acid 8-hydroxy-9-oxo-9,10-dihydro-anthracen...)
Affinity DataIC50:  6.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041773(1,8-Dihydroxy-2-[3-(3,4,5-trimethoxy-phenyl)-propy...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060901(1,8-Dihydroxy-2-propionyl-10H-anthracen-9-one | CH...)
Affinity DataIC50:  6.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041789(1,8-Dihydroxy-2-(4-hydroxy-benzyl)-10H-anthracen-9...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060859(4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracene-9-car...)
Affinity DataIC50:  7.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041802(1,8-dihydroxy-9(10H)-anthracenone | 1,8-dihydroxy-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory concentration against arachidonic acid 5-lipoxygenationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041804(3-(2,4-Dihydroxy-benzyl)-1,8-dihydroxy-10H-anthrac...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060856(4,5-Dimethoxy-10H-anthracen-9-one | CHEMBL125822)
Affinity DataIC50:  8.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060899(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracene-2-carb...)
Affinity DataIC50:  8.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060868(Acetic acid 8-acetoxy-9-oxo-9,10-dihydro-anthracen...)
Affinity DataIC50:  9.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060873(1,5-Dihydroxy-10H-anthracen-9-one | CHEMBL333452)
Affinity DataIC50:  1.00E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060900(1,8,9-Trimethoxy-9,10-dihydro-anthracene | CHEMBL1...)
Affinity DataIC50:  1.00E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041808(1,8-Dihydroxy-2-(3-phenyl-propyl)-10H-anthracen-9-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060886(1-Hydroxy-8-methoxy-10H-anthracen-9-one | CHEMBL12...)
Affinity DataIC50:  1.20E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060887(1-(2-Acetyl-benzyloxy)-8-hydroxy-10H-anthracen-9-o...)
Affinity DataIC50:  1.20E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060879(1-Hydroxy-10H-anthracen-9-one | CHEMBL123161)
Affinity DataIC50:  1.30E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060878(1,3,8-Trihydroxy-6-methyl-10H-anthracen-9-one | CH...)
Affinity DataIC50:  1.40E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM24777(5-hydroxy-1,4-dihydronaphthalene-1,4-dione | 5-hyd...)
Affinity DataIC50:  1.70E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060870(10-Acetyl-1,8-dihydroxy-10H-anthracen-9-one | CHEM...)
Affinity DataIC50:  1.80E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041792(2-Benzoyl-1,8-dihydroxy-10H-anthracen-9-one | CHEM...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060889(4-Amino-10H-anthracen-9-one | CHEMBL124264)
Affinity DataIC50:  2.00E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060890(10-Dimethylaminomethylene-1,8-dihydroxy-10H-anthra...)
Affinity DataIC50:  2.10E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060869(1,3,8-Trihydroxy-6-methyl-4,5-bis-(3-methyl-but-2-...)
Affinity DataIC50:  2.50E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060850(1-Benzoyl-8-hydroxy-10H-anthracen-9-one | CHEMBL42...)
Affinity DataIC50:  2.70E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50060864(1-Amino-10H-anthracen-9-one | CHEMBL122386)
Affinity DataIC50:  2.80E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041772(2-Benzyl-1,8-dihydroxy-10H-anthracen-9-one | CHEMB...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041777(1,8-Dihydroxy-3-(4-hydroxy-benzyl)-10H-anthracen-9...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50041779(1,8-Dihydroxy-3-(4-methoxy-benzyl)-10H-anthracen-9...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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