TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of W£Rzburg
Curated by ChEMBL
University Of W£Rzburg
Curated by ChEMBL
Affinity DataKi: 7.94E+3nMAssay Description:Binding affinity to muscarinic M1 acetylcholine receptor (unknown origin)More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of W£Rzburg
Curated by ChEMBL
University Of W£Rzburg
Curated by ChEMBL
Affinity DataKi: 1.26E+4nMAssay Description:Binding affinity to muscarinic M1 acetylcholine receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of kidney-type glutaminase in human BT20 cells assessed as reduction in glutamate levelMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of kidney-type glutaminase in human BT20 cells assessed as reduction in glutamate levelMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of kidney-type glutaminase in human BT20 cells assessed as reduction in glutamate levelMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of kidney-type glutaminase in human BT20 cells assessed as reduction in glutamate levelMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of GAC (unknown origin) assessed as NADH formation using 10 mM glutamine as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human KGA (63 to 669 residues) preincubated for 15 mins using 50 mM glutamine as substrate by resorufin dye based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human KGA (63 to 669 residues) preincubated for 15 mins using 50 mM glutamine as substrate by resorufin dye based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of GAC (unknown origin) assessed as NADH formation using 10 mM glutamine as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human KGA (63 to 669 residues) preincubated for 15 mins using 50 mM glutamine as substrate by resorufin dye based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Compounds were tested for their ability to inhibit separase enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Compounds were tested for their ability to inhibit separase enzyme.More data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human KGA (63 to 669 residues) preincubated for 15 mins using 50 mM glutamine as substrate by resorufin dye based assayMore data for this Ligand-Target Pair
Affinity DataIC50: <25nMAssay Description:Inhibition of mouse kidney glutaminase assessed as ammonia formation at 0.1 uM using glutamine as substrate by Nessler's reagent based assay relative...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human glutamate carboxypeptidase 2 (44 to 750 residues) overexpressed in Drosophila Schneider S2 cells using [3H]-NAAG/NAAG...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human KGA (63 to 669 residues) preincubated for 15 mins using 50 mM glutamine as substrate by resorufin dye based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human KGA (63 to 669 residues) preincubated for 15 mins using 50 mM glutamine as substrate by resorufin dye based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:Inhibition of mouse kidney glutaminase assessed as ammonia formation at 0.1 uM using glutamine as substrate by Nessler's reagent based assay relative...More data for this Ligand-Target Pair