Affinity DataIC50: 0.420nMAssay Description:Inhibition of human HDAC6 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated for 1 hr by fluor de lys substrate based fluorescence methodMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated for 1 hr by fluor de lys substrate based fluorescence methodMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human HDAC1 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human HDAC3 complexed with NCOR2 using fluorogenic tetrapeptide RHKKAc as susbtrateMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human HDAC4 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human HDAC11 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human HDAC5 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human HDAC10 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human HDAC7 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human HDAC6 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in sf9 cells using RHK-K(Ac)-AMC as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged HDAC7 (518 to 991 residues) expressed in insect cells using RHK-K(Ac)-AMC as substrate incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human HDAC7 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human HDAC6 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human HDAC9 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC8 (unknown origin) incubated for 1 hr by fluor de lys substrate based fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human HDAC6 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of HDAC6 (unknown origin) incubated for 1 hr by fluor de lys substrate based fluorescence methodMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human HDAC8 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human HDAC8 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC2 in human HeLa cells using KI-104 as substrate after 40 mins by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant HDAC2 using Fluor de Lys Green as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human HDAC2 after 40 mins by fluorescence analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human HDAC8 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of HDAC8 (unknown origin) incubated for 1 hr by fluor de lys substrate based fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of human HDAC8 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant C-terminal His-tagged HDAC8 (1 to 377 residues) expressed in insect cells using RHK-K(Ac)-AMC as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of full length human recombinant C-terminal FLAG-His-tagged HDAC1 (1 to 482 residues) expressed in sf21 cells using RHK-K(Ac)-AMC as subst...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Ronzoni Institute For Chemical And Biochem. Research
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of human HDAC1 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using BOC-Ac-Lys-AMC as substrate incubated for 90 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 281nMAssay Description:Inhibition of HDAC6 (unknown origin) incubated for 1 hr by fluor de lys substrate based fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of human HDAC9 using RHK-K(Ac)-AMC as substrate incubated for 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of human HDAC9 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
University Of Milan
Curated by ChEMBL
University Of Milan
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of full length human recombinant C-terminal His-tagged HDAC3 (1 to 428 residues)/human recombinant N-terminal GST-tagged NCOR2 (395 to 489...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of human HDAC3 complexed with NCOR2 using fluorogenic tetrapeptide RHKKAc as susbtrateMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant N-terminal His-tagged HDAC11 (1 to 347 residues) using RHK-K(Ac)-AMC as substrate incubated for 60 mins by fluorescen...More data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of human HDAC11 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of human HDAC5 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant C-terminal His-tagged HDAC5 (657 to 1123 residues) expressed in insect cells using RHK-K(Ac)-AMC as substrate incubat...More data for this Ligand-Target Pair
Affinity DataIC50: 409nMAssay Description:Inhibition of human HDAC6 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 459nMAssay Description:Inhibition of human HDAC10 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair