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Found 31 with Last Name = 'zuliani' and Initial = 'v'
TargetMelatonin receptor type 1A(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataKi:  0.166nMAssay Description:Binding Affinity (pKi) towards human Melatonin receptor type 1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1B(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataKi:  0.295nMAssay Description:Binding Affinity (pKi) towards human Melatonin receptor type 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50066960(CHEMBL33700 | N-(2-(5-methoxy-1-methyl-1H-indol-3-...)
Affinity DataKi:  1.70nMAssay Description:Binding Affinity (pKi) towards human Melatonin receptor type 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50066960(CHEMBL33700 | N-(2-(5-methoxy-1-methyl-1H-indol-3-...)
Affinity DataKi:  2.20nMAssay Description:Binding Affinity (pKi) towards human Melatonin receptor type 1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50471835(CHEMBL34327)
Affinity DataKi:  6.5nMAssay Description:Binding Affinity (pKi) towards human Melatonin receptor type 1BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50471830(CHEMBL33869)
Affinity DataKi:  135nMAssay Description:Binding Affinity (pKi) towards human Melatonin receptor type 1BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50471835(CHEMBL34327)
Affinity DataKi:  141nMAssay Description:Binding Affinity (pKi) towards Melatonin receptor type 1AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50471830(CHEMBL33869)
Affinity DataKi:  182nMAssay Description:Binding Affinity (pKi) towards human Melatonin receptor type 1AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50259542(2-(3-Trifluoromethylphenyl)-4(5)-(3-trifluoromethy...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50187134((E)-5-(4-Hydroxybenzylidene)-1-phenethylhydantoin ...)
Affinity DataIC50:  710nMAssay Description:Inhibition of EGFR-mediated polyGAT phosphorylation at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50259388(2-(4-Chlorophenyl)-4(5)-phenylimidazole | CHEMBL50...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50259490(2-Phenyl-4(5)-(4-trifluoromethylphenyl)imidazole |...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50259541(2-(4-Nitrophenyl)-4(5)-(3-trifluoromethylphenyl)-i...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50145044(2-Phenyl-4(5)-(3-trifluoromethylphenyl)imidazole |...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50330764(2-(4-Trifluoromethylphenyl)-4(5)-phenylimidazole |...)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50330765(2-Phenyl-4(5)-(3-chlorophenyl)imidazole | 4-(3-chl...)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50187134((E)-5-(4-Hydroxybenzylidene)-1-phenethylhydantoin ...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of EGFR autophosphorylation in human A549 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Rattus norvegicus)
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Curated by ChEMBL
LigandPNGBDBM50330763(2-(4-Methoxyphenyl)-4(5)-phenylimidazole | 2-(4-me...)
Affinity DataIC50:  1.96E+4nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50330763(2-(4-Methoxyphenyl)-4(5)-phenylimidazole | 2-(4-me...)
Affinity DataIC50:  2.14E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Rattus norvegicus)
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Curated by ChEMBL
LigandPNGBDBM50392415(CHEMBL402642)
Affinity DataIC50:  2.85E+4nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Rattus norvegicus)
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Curated by ChEMBL
LigandPNGBDBM50392416(CHEMBL2151778)
Affinity DataIC50:  3.17E+4nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Rattus norvegicus)
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Curated by ChEMBL
LigandPNGBDBM50133778(2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...)
Affinity DataIC50:  3.22E+4nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133778(2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...)
Affinity DataIC50:  4.06E+4nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133778(2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...)
Affinity DataIC50:  4.06E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50392417(CHEMBL2151781)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Rattus norvegicus)
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Curated by ChEMBL
LigandPNGBDBM50392418(CHEMBL2151783)
Affinity DataIC50:  5.36E+4nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50003655(Phenytoin)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50031299(6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50003655(Phenytoin)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50259540(2-(4-Chlorophenyl)-4(5)-(3-trifluoromethylphenyl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50351882(CHEMBL1825043)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed