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Target
Melatonin receptor type 1B
Ligand
BDBM50471830
Substrate
n/a
Meas. Tech.
ChEMBL_105272 (CHEMBL858415)
Ki
135±n/a nM
Citation
 Rivara, S; Mor, M; Silva, C; Zuliani, V; Vacondio, F; Spadoni, G; Bedini, A; Tarzia, G; Lucini, V; Pannacci, M; Fraschini, F; Plazzi, PV Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation. J Med Chem 46:1429-39 (2003) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50471830
Synonyms:
CHEMBL33869
Type:
Small organic molecule
Emp. Form.:
C19H20N2O2
Mol. Mass.:
308.3743
SMILES:
COc1ccc2n(cc(CCNC(C)=O)c2c1)-c1ccccc1
Structure:
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