TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 8.20nMAssay Description:Competitive inhibition of CDK6/cyclin D3 (unknown origin) assessed as phosphorylation of CTRF after 50 mins by Michaelis-Menten plot analysis in pres...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity against Glutamate RacemaseMore data for this Ligand-Target Pair
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Competitive irreversible inhibition of CDK7/cyclinH/MAT1 (unknown origin) using 5-FAM YSPTSPSYSPTSPSYSPTSPSKKKK as substrateMore data for this Ligand-Target Pair
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Competitive irreversible inhibition of CDK7/cyclinH/MAT1 (unknown origin) using 5-FAM YSPTSPSYSPTSPSYSPTSPSKKKK as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 85nMAssay Description:Inhibition of [3H]LY-341,495 binding to recombinant human mGlu2 receptorsMore data for this Ligand-Target Pair
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 105nMAssay Description:Competitive irreversible inhibition of CDK7/cyclinH/MAT1 (unknown origin) using 5-FAM YSPTSPSYSPTSPSYSPTSPSKKKK as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 126nMAssay Description:Inhibition of [3H]LY-341,495 binding to recombinant human mGlu3 receptorsMore data for this Ligand-Target Pair
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 255nMAssay Description:Competitive irreversible inhibition of CDK7/cyclinH/MAT1 (unknown origin) using 5-FAM YSPTSPSYSPTSPSYSPTSPSKKKK as substrateMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]LY-341,495 binding to recombinant human mGlu3 receptorsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]LY-341,495 binding to recombinant human mGlu2 receptorsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]LY-341,495 binding to mGlu2 receptors of rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+7nMAssay Description:Inhibition of [3H]LY-341,495 binding to mGlu2 receptors of rat brainMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human CDK4/cyclinD1More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK4 (unknown origin) using GST-fused pRb (792 to 928) as substrate preincubated for 2 mins followed by [gamma-32P]-ATP addition measur...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK4 (unknown origin) using GST-fused pRb (792 to 928) as substrate preincubated for 2 mins followed by [gamma-32P]-ATP addition measur...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Competitive reversible inhibition of recombinant full-length His-tagged human CDK9/cyclin T expressed in baculovirus infected insect cells using biot...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Competitive reversible inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Competitive inhibition of human CDK7 in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: <4nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human CDK6/cyclin D3More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Competitive reversible inhibition of recombinant full-length His-tagged human CDK9/cyclin T expressed in baculovirus infected insect cells using biot...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human CDK1/cyclin B1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK4 (unknown origin) using GST-fused pRb (792 to 928) as substrate preincubated for 2 mins followed by [gamma-32P]-ATP addition measur...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Competitive reversible inhibition of CDK2/cyclin E (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:In vitro inhibitory concentration against Cytochrome P450 3A4More data for this Ligand-Target Pair