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Found 120 with Last Name = 'de pascual-teresa' and Initial = 'b'
TargetInterstitial collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028942(CHEMBL1235735)
Affinity DataKi:  23nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
TargetMatrilysin(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028945(CHEMBL1738911)
Affinity DataKi:  79nMAssay Description:Inhibition of MMP7 (unknown origin)More data for this Ligand-Target Pair
TargetMatrilysin(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028944(CHEMBL1738910)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of MMP7 (unknown origin)More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50265079((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50539774(CHEMBL4648157)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028940(CHEMBL3359657)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50539771(CHEMBL4649511)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50539773(CHEMBL4637274)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028941(CHEMBL3359658)
Affinity DataIC50:  3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50539771(CHEMBL4649511)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50539769(CHEMBL4637423)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50539773(CHEMBL4637274)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Universidad San Pablo Ceu

LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  6nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-33P] ATP. 33...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM16596(4-N,6-N-bis[(4-fluoro-3-methylphenyl)methyl]pyrimi...)
Affinity DataIC50:  8nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50539771(CHEMBL4649511)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant HDAC6 using fluorogenic substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50539770(CHEMBL4645915)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50539773(CHEMBL4637274)
Affinity DataIC50:  16nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50539774(CHEMBL4648157)
Affinity DataIC50:  19nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50539772(CHEMBL4637976)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Universidad De Alcal£

Curated by ChEMBL
LigandPNGBDBM50466120(CHEMBL4277595)
Affinity DataIC50:  20nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50234334(BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...)
Affinity DataIC50:  30nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human recombinant HDAC6 expressed in Escherichia coli BL21(DE3) cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human recombinant HDAC1 expressed in Escherichia coli BL21(DE3) cells using KL177 as substrate preincubated for 5 followed by substrate...More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028943(CHEMBL3359656)
Affinity DataIC50:  40nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028940(CHEMBL3359657)
Affinity DataIC50:  44nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Universidad De Alcal£

Curated by ChEMBL
LigandPNGBDBM50084655(CHEMBL92708 | Calpeptin | Z-Leu-Nle-CHO | [(S)-1-(...)
Affinity DataIC50:  52nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase zeta(Homo sapiens)
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50464775(CHEMBL4278170)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant PTPRZ1 using pNPP as substrate by fluorescence spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase zeta(Homo sapiens)
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50464778(CHEMBL4285054)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant PTPRZ1 using pNPP as substrate by fluorescence spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50539772(CHEMBL4637976)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50539770(CHEMBL4645915)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50539769(CHEMBL4637423)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028941(CHEMBL3359658)
Affinity DataIC50:  346nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Universidad De Alcal£

Curated by ChEMBL
LigandPNGBDBM50466123(CHEMBL4281019)
Affinity DataIC50:  350nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Universidad De Alcal£

Curated by ChEMBL
LigandPNGBDBM50466128(CHEMBL4277940)
Affinity DataIC50:  380nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Universidad San Pablo Ceu

LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  400nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-33P] ATP. 33...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Universidad De Alcal£

Curated by ChEMBL
LigandPNGBDBM50466121(CHEMBL4285250)
Affinity DataIC50:  460nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50470579(4sc-202 | Domatinostat)
Affinity DataIC50:  600nMAssay Description:Inhibition of KDM1A/LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50464775(CHEMBL4278170)
Affinity DataIC50:  700nMAssay Description:Inhibition of human recombinant PTP1B using pNPP as substrate by fluorescence spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  776nMAssay Description:Inhibition of human recombinant HDAC8 expressed in Escherichia coli BL21(DE3) cells using Boc-Lys(TFA)-AMC as substrate preincubated for 5 followed b...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase zeta(Homo sapiens)
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50464773(CHEMBL4286807)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant PTPRZ1 using pNPP as substrate by fluorescence spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant HDAC4 expressed in Escherichia coli BL21(DE3) cells using Boc-Lys(TFA)-AMC as substrate preincubated for 5 followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Universidad De Alcal£

Curated by ChEMBL
LigandPNGBDBM50466124(CHEMBL4287411)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Universidad De Alcal£

Curated by ChEMBL
LigandPNGBDBM50466125(CHEMBL4283272)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Universidad De Alcal£

Curated by ChEMBL
LigandPNGBDBM50466127(CHEMBL4288918)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Universidad De Alcal£

Curated by ChEMBL
LigandPNGBDBM50466129(CHEMBL4290527)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad San Pablo-Ceu

Curated by ChEMBL
LigandPNGBDBM50464772(CHEMBL4293314)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant PTP1B using pNPP as substrate by fluorescence spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Universidad De Alcal£

Curated by ChEMBL
LigandPNGBDBM50466122(CHEMBL4285540)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Universidad De Alcal£

Curated by ChEMBL
LigandPNGBDBM50466130(CHEMBL4279497)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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