Affinity DataIC50: >100nMAssay Description:Inhibition of human serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: >100nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University
Curated by ChEMBL
Northern Illinois University
Curated by ChEMBL
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of recombinant full length human N-terminal GST/His6-tagged methionine aminopeptidase 2 expressed in baculovirus infected sf9 cells using ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University
Curated by ChEMBL
Northern Illinois University
Curated by ChEMBL
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of human methionine aminopeptidase 2More data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT (unknown origin)More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
U.S. Army Medical Research Institute Of Infectious Diseases
Curated by ChEMBL
U.S. Army Medical Research Institute Of Infectious Diseases
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of protease activity of recombinant full length Clostridium botulinum Hall BoNT/A light chain using SNAP-25 peptide (187 to 203 residues) ...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University
Curated by ChEMBL
Northern Illinois University
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human MetAP2 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University
Curated by ChEMBL
Northern Illinois University
Curated by ChEMBL
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of recombinant full length human His-tagged methionine aminopeptidase 1 expressed in Escherichia coli BL21(DE3) using methionylprolyl-p-ni...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University
Curated by ChEMBL
Northern Illinois University
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human methionine aminopeptidase 1More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University
Curated by ChEMBL
Northern Illinois University
Curated by ChEMBL
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of human MetAP1More data for this Ligand-Target Pair
TargetBotulinum neurotoxin type A(Clostridium botulinum)
U.S. Army Medical Research Institute Of Infectious Diseases
Curated by ChEMBL
U.S. Army Medical Research Institute Of Infectious Diseases
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Clostridium botulinum BoNT/A LC expressed in Escherichia coli assessed as cleavage of SNAPtide preincubated for 5 mins followed by SNAP...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Emory University
Curated by PubChem BioAssay
Emory University
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
University of California San Diego
Curated by ChEMBL
University of California San Diego
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...More data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Activx Biosciences
Curated by ChEMBL
Activx Biosciences
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...More data for this Ligand-Target Pair
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
University of California San Diego
Curated by ChEMBL
University of California San Diego
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Activx Biosciences
Curated by ChEMBL
Activx Biosciences
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...More data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
Anshan Normal University
Curated by ChEMBL
Anshan Normal University
Curated by ChEMBL
Affinity DataIC50: 1.10E+5nMAssay Description:Antibacterial activity against Enterococcus faecalis MTCC 439 incubated overnight by broth dilution techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Ewha Womans University
Curated by ChEMBL
Ewha Womans University
Curated by ChEMBL
Affinity DataIC50: 2.08E+5nMAssay Description:Inhibition of recombinant human QC using H-Gln-AMC hydrobromide as fluorogenic substrate incubated for 6 hrs by fluorometric microplate reader analys...More data for this Ligand-Target Pair
TargetFructose-bisphosphate aldolase(Mycobacterium tuberculosis (strain H37Rv))
The University of Denver and Regis University
US Patent
The University of Denver and Regis University
US Patent
Affinity DataIC50: 3.00E+5nMAssay Description:Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of Bacillus thermoproteolyticus thermolysinMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research
Curated by ChEMBL
Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 7.50E+5nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair