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Found 3 of ic50 for monomerid = 50076126
LigandPNGBDBM50076126((S)-2-({5-[(1H-Imidazol-4-ylmethyl)-amino]-bipheny...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of [3H]-GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50076126((S)-2-({5-[(1H-Imidazol-4-ylmethyl)-amino]-bipheny...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro inhibition of [3H]-FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076126((S)-2-({5-[(1H-Imidazol-4-ylmethyl)-amino]-bipheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed