Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ic50 for monomerid = 50545020
TargetSmoothened homolog(Mus musculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545020(LY-2940680 | LY2940680 | Taladegib)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of SMO in mouse 3T3/HH FlashII-7 cells incubated for 36 hrs in presence of SHH by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
TargetSmoothened homolog(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545020(LY-2940680 | LY2940680 | Taladegib)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
TargetSmoothened homolog(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545020(LY-2940680 | LY2940680 | Taladegib)
Affinity DataIC50:  400nMAssay Description:Antagonist activity at resistant Smo D473H mutant (unknown origin) in presence of GDC0449More data for this Ligand-Target Pair