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Found 3 Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50243388'
TargetAurora kinase B(Homo sapiens (Human))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50243388(AT-9283 | US10981896, Compound AT9283)
Affinity DataIC50:  30nMAssay Description:Inhibition of Aurora B kinase in human HCT116 cells assessed as reduction in polyploid phenotypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50243388(AT-9283 | US10981896, Compound AT9283)
Affinity DataIC50:  30nMAssay Description:Inhibition of Aurora B in human B-NHL cells assessed as inhibition of histone H3 phosphorylation on Ser10 by immunoblotting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50243388(AT-9283 | US10981896, Compound AT9283)
Affinity DataIC50:  62nMAssay Description:Inhibition of Aurora B (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed