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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM345135'
Target
Tyrosine-protein kinase SYK
(Homo sapiens (Human))
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US Patent
Ligand
BDBM345135
(1-[4-[2-(1H-Indazol-5-ylamino)pyrimidin-4-yl]oxy-1...)
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Affinity Data
IC50: 673nM
Assay Description:
The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...
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Target Info
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Reactome pathway
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Ligand Info
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US Patent
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