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Found 2 Enz. Inhib. hit(s) with Target = '15-hydroxyprostaglandin dehydrogenase [NAD(+)]' and Ligand = 'BDBM118073'
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM118073(CHEMBL2414145 | US8637558, 108)
Affinity DataIC50:  99nMAssay Description:Inhibition of human GST-fused 15-PGDH expressed in Escherichia coli BL21 using PGE2 as substrate assessed as formation of NADH by fluorescence spectr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM118073(CHEMBL2414145 | US8637558, 108)
Affinity DataIC50:  99.3nMpH: 7.5Assay Description:Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...More data for this Ligand-Target Pair
In DepthDetails US Patent