Found 52 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2A' and Ligand = 'BDBM50001885' Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in CRL:CD(SD)BR-COBS rat cortex by scintillation spectrometryMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.150nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Affinity DataKi: 0.160nMAssay Description:Ability to inhibit the binding of iodine-125-labelled lysergic acid diethylamide([125I]-LSD) to the S-2A serotonin receptor.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.160nMAssay Description:Binding affinity towards human serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat brainMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.170nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Affinity DataKi: 0.180nMAssay Description:Displacement of [3H]-ketanserine from serotonin 5-HT2A receptor in rat brain cortex homogenates incubated for 30 mins by liquid scintillation countin...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Affinity DataKi: 0.180nMAssay Description:Displacement of [3H] ketanserin from 5-HT2A receptor in Sprague-Dawley rat cerebral cortex incubated for 30 mins by liquid scintillation counting ana...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.190nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]ketanserin from rat cerebral cortex 5HT2A receptor measured after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Affinity DataKi: 0.200nMAssay Description:In vitro ability to displace [3H]ketanserin binding from 5-hydroxytryptamine 2A receptor in rat striatal membrane.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.290nMAssay Description:Binding affinity to human cloned 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.300nMAssay Description:The affinity of ligands was determined via radioligand binding techniques using human recombinant receptors expressed in mammalian clonal cells. Deta...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]ketanserine from 5-HT2A receptor in rat cerebral cortex homogenates after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 cell membranes measured after 30 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.390nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.390nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.5nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2AR expressed in CHO-K1 cell membranes after 1.5 hrs by microbeta counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]ketanserin from human cloned 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]ketanserin human cloned serotonin 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.501nMAssay Description:Binding affinity towards serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Affinity DataKi: 0.700nMAssay Description:Binding affinity measured at the 5-hydroxytryptamine 2A receptor by the inhibition of [3H]-ketanserin binding to rat cortex using unlabeled mianserin...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.810nMAssay Description:Inhibition of [125I]-R91150 binding to human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 1nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 1nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cell membrane after 60 mins by liquid scintillation countin...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Affinity DataKi: 3.55nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataIC50: 0.708nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataIC50: 0.720nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [3H]-ketanserin binding to rat frontal cortex membrane 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Janssen Research Foundation
Curated by PDSP Ki Database
Janssen Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 2.60nMAssay Description:In vitro affinity towards 5-hydroxytryptamine 2A receptor using [3H]-spiroperidol as radioligand in cortexMore data for this Ligand-Target Pair
