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Found 3 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM34156'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universitat De Barcelona

LigandPNGBDBM34156(indenylsulfonamide, 28)
Affinity DataKi:  3nM ΔG°:  -50.6kJ/mole IC50:  1.60E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universitat De Barcelona

LigandPNGBDBM34156(indenylsulfonamide, 28)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universitat De Barcelona

LigandPNGBDBM34156(indenylsulfonamide, 28)
Affinity DataIC50:  1.58E+3nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in HEK293F cells assessed as inhibition of 5HT-stimulated cAMP production after 30 mins by HTRF ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed