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Found 2 Enz. Inhib. hit(s) with Target = 'Activin receptor type-1' and Ligand = 'BDBM50466183'
TargetActivin receptor type-1(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50466183(CHEMBL4283638)
Affinity DataIC50:  9nMAssay Description:Inhibition of ALK2 (unknown origin) using Ulight topo IIa (Thr 1342) peptide as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50466183(CHEMBL4283638)
Affinity DataEC50:  8nMAssay Description:Inhibition of BMP6-induced ALK2 transcriptional activity in mouse C2C12 cells expressing BRE-Luc after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed