Found 70 Enz. Inhib. hit(s) with Target = 'Amine oxidase [flavin-containing] B' and Ligand = 'BDBM10989'
Affinity DataKi: 7.60nMAssay Description:Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human recombinant microsomal MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 min...More data for this Ligand-Target Pair
Affinity DataKi: 700nM ΔG°: -35.1kJ/molepH: 7.5 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically at 316 nm and 250 nm using kynuramine and benzylamine as substrates, respectively. ...More data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:Inhibition constant against human recombinant Monoamine oxidase-B More data for this Ligand-Target Pair
Affinity DataKi: 700nM ΔG°: -35.1kJ/molepH: 7.5 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically at 316 nm and 250 nm using kynuramine and benzylamine as substrates, respectively. ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:MAO-A and MAO-B activity was measured using radioactive substrates. The substrate for MAO-A was 5 HT and for MAO-B was PEA. When measuring the activi...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of Sprague-Dawley rat liver MAO-B using p-tyramine as substrate preincubated for 15 mins and measured after 45 mins by resorufin-based flu...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of rat brain MAO-B using [14C]-phenylethylamine substrate after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of MAO-B in rat brain using [14C]-phenylethylamine as substrate preincubated for 60 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of rat brain MAO-B using [14C]-phenylethylamine as substrate preincubated for 60 mins followed by substrate addition and measured after 20...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human MAO-BMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human MAO-BMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate assessed as decrease in H2O2 production incubated for 15 mins by fluorimetric met...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 60 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured over 15 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 30 mins by fluorimetric ...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus infected in BTI cells using kynuramine as substrate after 30 mins by fluorescence based...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant MAOB assessed as H2O2 production by Amplex Red reagent-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human brain MAO-B using [14C]-phenylethylamine substrate after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Irreversible inhibition of human MAOBMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Irreversible inhibition of human cerebral cortex MAO-B using [14C]-phenylethylamin as substrate pretreated for 60 mins followed by substrate addition...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 30 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human MAOB using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human MAO-B expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI cells using p-tyramine as substrate by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 30 mins by fluorescence ...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 30 mins by fluorescence ...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant MAO-B by multimode plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using kynuramine as substrate incubated for 30 mins by fluor...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using kynuramine as substrate measured after 30 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human microsomal MAOB expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant MAO-B using kynuramine as substrate measured after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant microsomal MAO-B expressed in baculovirus-infected BTI-TN-5B1-4 cells assessed as inhibition of H2O2 production using...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of MAO-B (unknown origin) incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B (5 mg/mL) were purchased from Sigma-Aldrich, pre-aliquoted and stored at -80 °C. Solutions of test compounds we...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human MAO-B using kynuramine as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using kynuramine as substrate measured after 30 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant MAO-B expressed in insect cells assessed as kynuramine hydrobromide oxidation after 20 mins by spectrophotometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI-TN- 5B1-4 insect cells using kynuramine as substrate preincubated for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human MAO-B expressed in insect cells using kynuramine as substrate assessed as formation of 4-hydroxyquinoline measured ev...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decrease in H2O2...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using tyramine as substrate pretreated for 30 mins followed ...More data for this Ligand-Target Pair