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Found 5 Enz. Inhib. hit(s) with Target = 'Amyloid beta-binding alcohol dehydrogenase' and Ligand = 'BDBM232927'
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)
Affinity DataKi:  1.49E+4nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)
Affinity DataKi:  7.06E+4nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)
Affinity DataIC50:  5.27E+4nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)
Affinity DataIC50:  2.59E+5nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)
Affinity DataKd:  291nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent