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Found 2 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM50485994'
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50485994(CHEMBL2203385)
Affinity DataIC50:  11nMAssay Description:Binding affinity to human amyloid beta plaqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50485994(CHEMBL2203385)
Affinity DataKd:  9.60nMAssay Description:Displacement of [3H]DMAB from amyloid beta plaque in cortex homogenate isolated from Alzheimer disease patient after 90 mins by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed