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Found 1 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein [672-713]' and Ligand = 'BDBM446490'
TargetAmyloid-beta precursor protein [672-713](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM446490(N2-(3-Fluoro-4-(5-methyl-1H-1,2,4-triazol-1-yl)phe...)
Affinity DataEC50:  22nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent