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Found 4 Enz. Inhib. hit(s) with Target = 'Arginase-1' and Ligand = 'BDBM50538518'
TargetArginase-1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50538518(CHEMBL4639162)
Affinity DataIC50:  29nMAssay Description:Inhibition of human arginase1 in presence of DNTB by thio ornithine generation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50538518(CHEMBL4639162)
Affinity DataIC50:  148nMAssay Description:Inhibition of arginase1 in human cancer patient serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50538518(CHEMBL4639162)
Affinity DataIC50:  361nMAssay Description:Inhibition of arginase1 in human HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-1(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50538518(CHEMBL4639162)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of arginase1 in mouse BMDM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed