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Found 2 Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM92810'
TargetAurora kinase A(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM92810(Bisanilinopyrimidine, 6c | US9249124, 26)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:Reactions were carried out at room temperature in 15 mM HEPES buffer (pH 7.4) containing 20 mM NaCl, 1 mM EGTA, 0.02% Tween 20, 10 mM MgCl2, 5% (v/v)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM92810(Bisanilinopyrimidine, 6c | US9249124, 26)
Affinity DataIC50:  2nMAssay Description:In vitro enzyme activity assay using Aurora Kinase A. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed