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Found 2 Enz. Inhib. hit(s) with Target = 'Baculoviral IAP repeat-containing protein 2' and Ligand = 'BDBM156137'
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM156137(US9018214, 188)
Affinity DataIC50:  40nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM156137(US9018214, 188)
Affinity DataEC50:  240nMAssay Description:Induction of cIAP1 degradation in human MDA-MB-231 cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed