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Found 5 Enz. Inhib. hit(s) with Target = 'Beta-2 adrenergic receptor' and Ligand = 'BDBM27958'
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27958(1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...)
Affinity DataKi:  570nM ΔG°:  -35.3kJ/mole IC50:  1.30E+3nM EC50:  6.20nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27958(1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...)
Affinity DataKd:  16nMAssay Description:Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-2 adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM27958(1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...)
Affinity DataKd:  18nMAssay Description:Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM27958(1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...)
Affinity DataKd:  37nMAssay Description:Apparent binding affinity constant to beta-2 adrenergic receptor determined using [3H]DHAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM27958(1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...)
Affinity DataKd:  36nMAssay Description:Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed