Found 57 Enz. Inhib. hit(s) with Target = 'Beta-lactamase' and Ligand = 'BDBM50053173' 
Affinity DataKi: 7.40E+4nMAssay Description:Inhibition of Klebsiella pneumoniae 1534 beta-lactamase KPC-2 by competitive assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+5nMAssay Description:Inhibition of Enterobacter cloacae beta-lactamase P99 after 5 seconds incubation with nitrocefin substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetBeta-lactamase(Escherichia coli)
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Escherichia coli CTX-M-15More data for this Ligand-Target Pair
TargetBeta-lactamase(Salmonella enterica subsp. enterica serovar Westha...)
Centre National De R£F£Rence Des Salmonella
Curated by ChEMBL
Centre National De R£F£Rence Des Salmonella
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of Salmonella enterica serotype Westhampton beta-lactamase CTX-M-53More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli beta-lactamase SCO1More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against Proteus vulgaris HJ33C Class-I beta-lactamase enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Enterobacter cloacae IMI1 beta lactamase expressed in Escherichia coli DH5alpha by SDS-PAGEMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against Class A (Imi-1) beta-LactamasesMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Citrobacter gillenii CIP 106783 Beta-lactamase GIL1 expressed in Escherichia coli DH10BMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Pseudomonas luteola LAM Beta-lactamase LUT-1More data for this Ligand-Target Pair
TargetBeta-lactamase(Enterobacter cloacae)
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against class A Beta-lactamase TEM isolated from Enterobacter coliMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of Pseudomonas aeruginosa GES-13 beta lactamaseMore data for this Ligand-Target Pair
TargetBeta-lactamase(Klebsiella pneumoniae)
National Institute Of Health Dr. Ricardo Jorge Av. Padre Cruz
Curated by ChEMBL
National Institute Of Health Dr. Ricardo Jorge Av. Padre Cruz
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Klebsiella pneumoniae Beta-Lactamase SHV-72More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 96nMAssay Description:Inhibition of Citrobacter freundii PER2 beta lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against Beta-lactamase TEM-1 of class A enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 106nMAssay Description:Inhibitory activity against Klebsiella oxytoca HC7 Class-IV K1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Compound was tested for inhibition of Beta-lactamase from RTEM-3More data for this Ligand-Target Pair
Affinity DataIC50: 166nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 166nMAssay Description:Inhibitory activity against Citrobacter freundii 87470 Class-I beta-lactamase enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Compound was tested for inhibition of beta-Lactamases from Morganell morgani U1627More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of Escherichia coli DH5alpha beta-lactamase TEM-158More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Compound was tested for inhibition of Beta-lactamase from OXA-1More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against class A TEM-1 beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 333nMAssay Description:Inhibitory activity against Enterobacter cloacae HC8 Class-I beta-lactamase enzyme type P99More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Compound was tested for inhibition of Beta-lactamase from RTEM-1More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Compound was tested for inhibition of Beta-lactamase from Staphylococcus aureus PCIMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of Burkholderia cenocepacia 07-34 beta-lactamase PenB1More data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Compound was tested for inhibition of Beta-lactamase from Bacillus licheniformis 749/CMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Compound was tested for inhibition of Beta-lactamase from RTEM-2More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Compound was tested for inhibition of Beta-lactamase from PSE-1More data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Compound was tested for inhibition of Beta-lactamase from Pseudomonas aeruginosa 18SHMore data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Compound was tested for inhibition of Beta-lactamase fromOXA-2More data for this Ligand-Target Pair
Affinity DataIC50: 930nMAssay Description:Compound was tested for inhibition of Beta-lactamase from SHV-2More data for this Ligand-Target Pair
Affinity DataIC50: 930nMAssay Description:Compound was tested for inhibition of Beta-lactamase from Citrobacter freundii 1982More data for this Ligand-Target Pair
Affinity DataIC50: 943nMAssay Description:Inhibitory activity against beta-Lactamase enzyme derived from Enterobacter cloacae P99More data for this Ligand-Target Pair
Affinity DataIC50: 950nMpH: 7.0Assay Description:For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Enterobacter cloacae beta-lactamase P99 assessed as nitrocefin hydrolysis after 5 mins enzyme-compound preincubationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 1.81E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Compound was tested for inhibition of Beta-lactamase from Enterobacter cloacae 908RMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa 531 beta-lactamase BEL-2More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa 51170 beta-lactamase BEL-1More data for this Ligand-Target Pair
Affinity DataIC50: 2.11E+3nMAssay Description:Compound was tested for inhibition of Beta-lactamase from Pseudomonas aeruginosa GN10362More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against beta-Lactamase enzyme derived from Enterobacter cloacae SC 12368 E-2More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa beta-lactamase AmpC assessed as nitrocefin hydrolysis after 5 mins enzyme-compound preincubationMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of Serratia fonticola UTAD54 SFC1 beta lactamase expressed in Escherichia coli BL21(DE3) by SDS-PAGEMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibitory activity against class C Beta-lactamase isolated from Enterobacter cloacaeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Compound was tested for inhibition of Beta-lactamase from Escherichia coli SN03More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+4nMAssay Description:Compound was tested for inhibition of Beta-lactamase from Pseudomonas aeruginosa MK-1184More data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+4nMAssay Description:In vitro inhibitory activity against Beta-lactamase AmpC of class C enzymeMore data for this Ligand-Target Pair
