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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50271769'
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50271769(1-benzyl-N-((1S,2S)-1-((S)-4-benzyl-3-oxopiperazin...)
Affinity DataIC50:  22nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50271769(1-benzyl-N-((1S,2S)-1-((S)-4-benzyl-3-oxopiperazin...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of BACE1 in HEK293 cells transfected with human APP cDNA containing Swedish ad London FAD mutant assessed as inhibition of amyloid beta 1-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed